Document Detail


Assessment of acute myocardial necrosis after cardiopulmonary resuscitation and cardioversion by means of combined thallium-201/technetium-99m pyrophosphate tomography.
MedLine Citation:
PMID:  8575479     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Diagnosis of acute myocardial necrosis by means of conventional electrocardiographic criteria or the release of cardiac enzymes is often difficult or even impossible in patients with out-of-hospital cardiac arrest due to ventricular fibrillation with subsequent cardiopulmonary resuscitation including several DC countershocks. Simultaneous thallium-201/technetium-99m pyrophosphate (PYP) tomography was prospectively applied to 57 patients without typical clinical or electrocardiographic signs of acute myocardial infarction within 48 h after successful resuscitation from out-of-hospital cardiac arrest. Scintigraphic evidence of acute necrosis was present in 23/57 patients (40%). Increased 99mTc-PYP uptake in the pericardial tissue was found in 24 patients (42%). Maximal creatine kinase (CK) concentration was increased in 50/57 patients (88%). CK-MB activity averaged 68+/-52 U/l in patients with positive and 17+/-13 U/l in patients with negative tomograms (P<0.0005), demonstrating the validity of 201Tl/99mTc-PYP tomography. It may be concluded that simultaneous 201Tl/99mTc-PYP tomography is a valuable tool for evaluation of myocardial necrosis after cardiopulmonary resuscitation including DC countershock. Acute myocardial necrosis, as indicated by scintigraphy, represents a potential trigger for the occurrence of ventricular fibrillation. Therefore, 201Tl/99mTc-PYP tomography can be recommended in order to guide further diagnostic and therapeutic interventions in patients after cardiopulmonary resuscitation in whom the underlying cause of the occurrence of ventricular fibrillation is obscure.
Authors:
T Krause; S H Hohnloser; W Kasper; C Schümichen; M Reinhardt; E Moser
Related Documents :
2312909 - Accidental hypothermia with cardiac arrest: complete recovery after prolonged resuscita...
11994869 - Arch reconstruction without circulatory arrest: current clinical applications and resul...
8959769 - Out-of-hospital cardiac arrest. evaluation of one year of activity in saint-etienne's e...
7798869 - Ontogeny of cardiac function in the brine shrimp artemia franciscana kellogg 1906 (bran...
2372169 - Cardiopulmonary bypass in a model of acute myocardial infarction and cardiac arrest.
16884509 - Microvolt t-wave alternans with exercise in pediatrics and congenital heart disease: li...
21392599 - Integrating the synergy between percutaneous coronary intervention with taxus and cardi...
1350489 - Pathophysiology and triggers of acute myocardial infarction: clinical implications.
616069 - The effect of mexiletine on the electrophysical properties of the intact human heart.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of nuclear medicine     Volume:  22     ISSN:  0340-6997     ISO Abbreviation:  Eur J Nucl Med     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-03-13     Completed Date:  1996-03-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7606882     Medline TA:  Eur J Nucl Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  1286-91     Citation Subset:  IM    
Affiliation:
Radiologische Universitätsklinik, Abteilung Nuklearmedizin, Freiburg, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Aged
Aged, 80 and over
Cardiopulmonary Resuscitation*
Creatine Kinase / blood
Electric Countershock*
Female
Heart / radionuclide imaging*
Humans
Isoenzymes
Male
Middle Aged
Myocardium / pathology*
Necrosis
Prospective Studies
Technetium Tc 99m Pyrophosphate / diagnostic use*
Thallium Radioisotopes / diagnostic use*
Ventricular Fibrillation / therapy
Chemical
Reg. No./Substance:
0/Isoenzymes; 0/Technetium Tc 99m Pyrophosphate; 0/Thallium Radioisotopes; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Delayed gastric emptying and Helicobacter pylori infection in patients with chronic renal failure.
Next Document:  Radionuclide angiography and magnetic resonance imaging: complementary non-invasive methods in the d...