| Assessment of acute myocardial necrosis after cardiopulmonary resuscitation and cardioversion by means of combined thallium-201/technetium-99m pyrophosphate tomography. | |
| | |
MedLine Citation:
|
PMID: 8575479 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Diagnosis of acute myocardial necrosis by means of conventional electrocardiographic criteria or the release of cardiac enzymes is often difficult or even impossible in patients with out-of-hospital cardiac arrest due to ventricular fibrillation with subsequent cardiopulmonary resuscitation including several DC countershocks. Simultaneous thallium-201/technetium-99m pyrophosphate (PYP) tomography was prospectively applied to 57 patients without typical clinical or electrocardiographic signs of acute myocardial infarction within 48 h after successful resuscitation from out-of-hospital cardiac arrest. Scintigraphic evidence of acute necrosis was present in 23/57 patients (40%). Increased 99mTc-PYP uptake in the pericardial tissue was found in 24 patients (42%). Maximal creatine kinase (CK) concentration was increased in 50/57 patients (88%). CK-MB activity averaged 68+/-52 U/l in patients with positive and 17+/-13 U/l in patients with negative tomograms (P<0.0005), demonstrating the validity of 201Tl/99mTc-PYP tomography. It may be concluded that simultaneous 201Tl/99mTc-PYP tomography is a valuable tool for evaluation of myocardial necrosis after cardiopulmonary resuscitation including DC countershock. Acute myocardial necrosis, as indicated by scintigraphy, represents a potential trigger for the occurrence of ventricular fibrillation. Therefore, 201Tl/99mTc-PYP tomography can be recommended in order to guide further diagnostic and therapeutic interventions in patients after cardiopulmonary resuscitation in whom the underlying cause of the occurrence of ventricular fibrillation is obscure. |
| | |
Authors:
|
T Krause; S H Hohnloser; W Kasper; C Schümichen; M Reinhardt; E Moser |
Related Documents
:
|
2312909 - Accidental hypothermia with cardiac arrest: complete recovery after prolonged resuscita... 11994869 - Arch reconstruction without circulatory arrest: current clinical applications and resul... 8959769 - Out-of-hospital cardiac arrest. evaluation of one year of activity in saint-etienne's e... 7798869 - Ontogeny of cardiac function in the brine shrimp artemia franciscana kellogg 1906 (bran... 2372169 - Cardiopulmonary bypass in a model of acute myocardial infarction and cardiac arrest. 16884509 - Microvolt t-wave alternans with exercise in pediatrics and congenital heart disease: li... 21392599 - Integrating the synergy between percutaneous coronary intervention with taxus and cardi... 1350489 - Pathophysiology and triggers of acute myocardial infarction: clinical implications. 616069 - The effect of mexiletine on the electrophysical properties of the intact human heart. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: European journal of nuclear medicine Volume: 22 ISSN: 0340-6997 ISO Abbreviation: Eur J Nucl Med Publication Date: 1995 Nov |
Date Detail:
|
Created Date: 1996-03-13 Completed Date: 1996-03-13 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7606882 Medline TA: Eur J Nucl Med Country: GERMANY |
Other Details:
|
Languages: eng Pagination: 1286-91 Citation Subset: IM |
Affiliation:
|
Radiologische Universitätsklinik, Abteilung Nuklearmedizin, Freiburg, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Adult Aged Aged, 80 and over Cardiopulmonary Resuscitation* Creatine Kinase / blood Electric Countershock* Female Heart / radionuclide imaging* Humans Isoenzymes Male Middle Aged Myocardium / pathology* Necrosis Prospective Studies Technetium Tc 99m Pyrophosphate / diagnostic use* Thallium Radioisotopes / diagnostic use* Ventricular Fibrillation / therapy |
| Chemical | |
Reg. No./Substance:
|
0/Isoenzymes; 0/Technetium Tc 99m Pyrophosphate; 0/Thallium Radioisotopes; EC 2.7.3.2/Creatine Kinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Delayed gastric emptying and Helicobacter pylori infection in patients with chronic renal failure.
Next Document: Radionuclide angiography and magnetic resonance imaging: complementary non-invasive methods in the d...