Document Detail


Assessment of mechanical properties of common carotid artery in Takayasu's arteritis using velocity vector imaging.
MedLine Citation:
PMID:  20453392     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Alteration of arterial elastic properties is known to occur in patients with arteritis. Velocity vector imaging (VVI) is a new technology to assess multi-dimensional regional mechanics in terms of velocity, strain, strain rate and displacement. The aim of the present study was to investigate the mechanical properties of the common carotid artery using VVI in patients with Takayasu's arteritis (TA).
METHODS AND RESULTS: Vascular properties of the carotid artery were assessed in 12 patients with TA (11 female, age 38+/-10 years) and 12 healthy age- and sex-matched controls. Velocity, strain, strain rate and displacement were decreased significantly in TA compared with controls. Standard deviations, however, of time to peak velocity (Tv), strain (Ts), strain rate (Tsr), and displacement (Td) of multiple arterial wall segments were significantly higher in TA (P<0.0001), suggesting disturbance of symmetric arterial expansion during systole. The severity of carotid stenosis was also positively correlated with standard deviations of Tv, Ts, Tsr and Td.
CONCLUSIONS: Arterial assessment using VVI may represent a new noninvasive method for quantifying vascular alteration associated with arteritis.
Authors:
In Jeong Cho; Chi Young Shim; Woo-In Yang; Sung-Ai Kim; Hyuk-Jae Chang; Yangsoo Jang; Namsik Chung; Jong-Won Ha
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-04-20
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  74     ISSN:  1347-4820     ISO Abbreviation:  Circ. J.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-30     Completed Date:  2010-10-19     Revised Date:  2011-02-18    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1465-70     Citation Subset:  IM    
Affiliation:
Cardiology Division, Yonsei Cardiovascular Center, Yonsei University College of Medicine, Seoul, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biomechanics
Carotid Artery, Common / pathology,  physiopathology*
Carotid Stenosis / diagnosis,  physiopathology
Case-Control Studies
Diagnostic Imaging / methods*
Female
Humans
Male
Middle Aged
Takayasu Arteritis / diagnosis,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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