Document Detail


Assessment of MR compatibility of a PET insert developed for simultaneous multiparametric PET/MR imaging on an animal system operating at 7 T.
MedLine Citation:
PMID:  20806353     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The combination of positron emission tomography and MR in one system is currently emerging and opens up new domains in the functional examinations of living systems. This article reports on relevant influences of a positron emission tomography insert on MR imaging. The basic conditions of main magnetic field and RF field homogeneity were measured as well as image quality and signal-to-noise ratio when applying the usual MR sequence types including echo-planar techniques. Moreover, the influence of the positron emission tomography insert on the RF noise level and on RF interferences was measured by comparing results achieved with and without the positron emission tomography insert. The temporal stability of EPI imaging with and without the positron emission tomography insert was assessed. Small but significant decreases in the signal-to-noise ratio were revealed when the positron emission tomography insert was present, whereas B(0) and B(1) homogeneity as well as RF noise level were not adversely affected. A higher signal intensity drift was found for EPI imaging studies; however, this can be compensated by post processing. In summary, this study shows that positron emission tomography inserts can be designed for and used within an MR system practically, without substantially affecting the MR image quality.
Authors:
Hans F Wehrl; Martin S Judenhofer; Axel Thielscher; Petros Martirosian; Fritz Schick; Bernd J Pichler
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine     Volume:  65     ISSN:  1522-2594     ISO Abbreviation:  Magn Reson Med     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-20     Completed Date:  2011-04-14     Revised Date:  2012-01-04    
Medline Journal Info:
Nlm Unique ID:  8505245     Medline TA:  Magn Reson Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  269-79     Citation Subset:  IM    
Copyright Information:
© 2010 Wiley-Liss, Inc.
Affiliation:
Laboratory for Preclinical Imaging and Imaging Technology of the Werner Siemens-Foundation, University of Tuebingen, Tuebingen, Germany. hans.wehrl@med.uni-tuebingen.de
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MeSH Terms
Descriptor/Qualifier:
Animals
Artifacts*
Equipment Design
Equipment Failure Analysis
Magnetic Resonance Imaging / instrumentation*,  veterinary*
Mice
Positron-Emission Tomography / instrumentation*,  veterinary*
Rats
Subtraction Technique / instrumentation*,  veterinary*
Grant Support
ID/Acronym/Agency:
1R21EB004483/EB/NIBIB NIH HHS; R21 EB004483-03/EB/NIBIB NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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