Document Detail

Assessment of left ventricular volumes and function by real time three-dimensional echocardiography in a pediatric population: a TomTec versus QLAB comparison.
MedLine Citation:
PMID:  20584067     Owner:  NLM     Status:  In-Process    
BACKGROUND: Three-dimensional echocardiography (3DE) allows accurate calculation of ventricular volumes despite a remaining geometric assumption on the ventricular shape. Few studies involving full volume reconstruction software have been performed on children. Our aim was to compare the left ventricular (LV) volume measurements obtained with the most used 3D analysis software in a pediatric population.
METHODS: Fifty patients (median age: 9.5 years) without cardiac disease were included in the study. 3DE was performed with the X4-2 or X7-2 matrix probe (ie33, Philips). The LV volume analysis was performed with QLAB 6.0 (semiautomated border detection) and TomTec 4D LV (primary manual tracking with semiautomated border detection).
RESULTS: TomTec analysis feasibility amounted to 94% whereas QLAB analysis feasibility only reached 80% (P = 0.037). The analysis time was shorter with QLAB than TomTec (5 ± 2 versus 6 ± 3 minutes, P < 0.05). The stroke volume, end diastolic and end systolic LV volume measurements performed on the 40 patients were strongly correlated (r > 0.97; P < 0.0001) with minimal bias. The LV ejection fraction was well correlated (r = 0.79; P < 0.0001).
CONCLUSION: 3D LV volume quantification is feasible either by using manual or automated reconstruction software in a normal pediatric population. LV Measurements are well correlated. Differences in volume reconstruction algorithms provide specific software performance characteristics. TomTec is a more feasible method but requires a longer analysis time. Further studies are needed to validate the accuracy of the method to calculate enlarged LV volumes in patients with congenital heart diseases.
Sébastien Hascoët; Gilles Brierre; Guillaume Caudron; Christelle Cardin; Vanina Bongard; Philippe Acar
Related Documents :
12939547 - Osteopontin is released from the heart into the coronary circulation in patients with a...
3773227 - Familial hypertrophic cardiomyopathy mimicing typical dilated cardiomyopathy.
8315817 - Combined assessment with myocardial contractility and an index related to ventricular a...
11676947 - Comparison of chronic biventricular pacing between epicardial and endocardial left vent...
19045527 - Modifying a tilting disk mechanical heart valve design to improve closing dynamics.
11074217 - Effect of heterozygosity for the methionine synthase 2756 a-->g mutation on the risk fo...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  27     ISSN:  1540-8175     ISO Abbreviation:  Echocardiography     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1263-73     Citation Subset:  IM    
Copyright Information:
© 2010, Wiley Periodicals, Inc.
Department of Paediatric Cardiology, Hôpital des Enfants, Université de Toulouse, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Impact of myocardial acceleration during isovolumic contraction in evaluating subclinical right vent...
Next Document:  Myocardial strain characterization in different left ventricular adaptative responses to high blood ...