| Assessment of left ventricular hypertrophy in a trained athlete: differential diagnosis of physiologic athlete's heart from pathologic hypertrophy. | |
| | |
MedLine Citation:
|
PMID: 22386289 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Physiologic LV remodeling in young trained athletes as a consequence of chronic training can occasionally mimic certain pathologic conditions associated with sudden death, such as HCM. A small but important subset of elite male athletes may show a borderline increased LV wall thickness of 13 to 15 mm, which defines a gray zone of overlap between the extreme expressions of athlete's heart and a mild HCM phenotype. Such diagnostic ambiguity can be resolved by using the paradigm of noninvasive parameters including testing with echocardiography (and, more recently, with CMR): left atrial and LV chamber dimensions and shape, brief periods of deconditioning to alter LV mass, measurement of oxygen consumption and diastolic filling, and recognition of familial occurrence of HCM or a pathogenic HCM-causing sarcomere mutation. Such distinctions between physiologic/benign athlete's heart and HCM, the most common cause of sudden death in the young in the United States, can be crucial. The recognition of HCM leads to disqualification from intense competitive sports to reduce sudden death risk and, when appropriate, permits initiation of therapeutic interventions. |
| | |
Authors:
|
Antonio Pelliccia; Martin S Maron; Barry J Maron |
Related Documents
:
|
22172779 - A randomized study of the beneficial effects of aldosterone antagonism on lv function, ... 20429699 - The association between metabolic syndrome and infarct size in patients with acute myoc... 22188799 - Influence of myocardial fibrosis on left ventricular hypertrophy in patients with sympt... 22527259 - Cardiac computed tomographic imaging to evaluate myocardial scarring/fibrosis in patien... 19241139 - A minimally invasive method for induction of myocardial infarction in an animal model u... 833899 - Predictive value of psychosocial profiles following aclte myocardial infarction. 16524539 - Metabolic modulation of myocardial ischemia. 1457309 - Apparent elevation of serum ck-mb not due to acute myocardial infarction. 1388979 - Clonidine in the treatment of brainstem spasticity. case report. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Progress in cardiovascular diseases Volume: 54 ISSN: 1873-1740 ISO Abbreviation: Prog Cardiovasc Dis Publication Date: 2012 Mar-Apr |
Date Detail:
|
Created Date: 2012-03-05 Completed Date: 2012-04-23 Revised Date: 2013-05-02 |
Medline Journal Info:
|
Nlm Unique ID: 0376442 Medline TA: Prog Cardiovasc Dis Country: United States |
Other Details:
|
Languages: eng Pagination: 387-96 Citation Subset: AIM; IM |
Copyright Information:
|
Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
|
The Institute of Sport Medicine and Science, Italian National Olympic Committee, Rome, Italy. ant.pelliccia@libero.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adaptation, Physiological Athletes* Cardiomyopathy, Hypertrophic / diagnosis*, etiology, pathology, physiopathology Diagnosis, Differential Exercise* Female Heart Ventricles / pathology, physiopathology* Humans Hypertrophy, Left Ventricular / diagnosis*, etiology, pathology, physiopathology Male Physical Endurance Predictive Value of Tests Risk Factors Ventricular Function, Left* Ventricular Remodeling* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Exercise-induced cardiac remodeling.
Next Document: Evaluation of suspected right ventricular pathology in the athlete.