Document Detail


Assessment of fatigue after blood transfusion in palliative care patients: a feasibility study.
MedLine Citation:
PMID:  20973677     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: Blood transfusions are often used as a potential treatment for cancer-related fatigue in anaemic palliative care patients. However, evidence of benefit using validated outcomes measures is lacking.
AIM: The aim of this study was to test the feasibility of using two such tools; the Brief Fatigue Inventory and FACT F-fatigue subscale, to measure change in fatigue following a blood transfusion.
METHOD: Anemic cancer patients receiving specialist palliative care and undergoing transfusion for fatigue, completed the tools pre- and 3 days post-transfusion.
RESULTS: Thirty patients with cancer-related fatigue who received a blood transfusion completed the study. Both measures were capable of detecting statistical and clinically significant change in fatigue following transfusion. Furthermore, the measures showed significant differences between patients that did, or did not, report an overall improvement in fatigue. Patients found the measures easy to complete with no preference for one over another. Future clinical trials of blood transfusion for the management of fatigue should incorporate these validated outcome measures.
Authors:
Elizabeth Brown; Adam Hurlow; Af Rahman; S Jose Closs; Michael I Bennett
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Publication Detail:
Type:  Journal Article     Date:  2010-10-25
Journal Detail:
Title:  Journal of palliative medicine     Volume:  13     ISSN:  1557-7740     ISO Abbreviation:  J Palliat Med     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808462     Medline TA:  J Palliat Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1327-30     Citation Subset:  IM    
Affiliation:
St. Michael's Hospice, Harrogate, UK. lbrown@saintmichaelshospice.org
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