Document Detail

Assessment of the effectiveness of pharmacotherapy follow-up in patients treated for depression.
MedLine Citation:
PMID:  23537456     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Several studies have established the effectiveness of pharmaceutical care (PC) in patients with heart failure, diabetes, hypertension, and dyslipidemia. However, there are few studies using standardized methods, e.g., randomized controlled trials, to assess the effectiveness of pharmacotherapy follow-up (PF) in patients with depression.
OBJECTIVE: To assess the effectiveness of PC via PF according to the Dáder Method in female patients diagnosed with depression.
METHODS: Sixty-eight patients were selected and randomly allocated to groups, stratified by age, type of medication, severity of depression, and presence of recurrence and/or relapse. Patients in the intervention group (IG) received clinical pharmacy intervention at monthly visits over a 3-month follow-up period. The control group (CG) also received monthly visits from the pharmacist, but PF intervention was not performed.
RESULTS: A comparison of the effects of usual treatment (CG) and PC (IG) on depressive symptoms showed a statistically significant difference between groups, with a median reduction in Beck Depression Inventory score (Δ) of 2.5 points in the CG and 13.5 points in the IG. Similarly, statistically significant results were observed for anxiety symptoms, with a median reduction in Beck Anxiety Inventory score (Δ) of 3.5 points in the CG and 13.0 points in the IG. The patients who underwent PF showed a high level of satisfaction with the service.
CONCLUSION: The PF is well accepted and effective in treating depressed patients, as indicated by the reduction of the depressive and anxious symptoms.
Luciene Alves Moreira Marques; José Carlos Fernandes Galduróz; Maria Rosana Fernandes; Cristiane Carneiro Oliveira Oliveira; Luiz Alberto Beijo; Ana Regina Noto
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of managed care pharmacy : JMCP     Volume:  19     ISSN:  1083-4087     ISO Abbreviation:  J Manag Care Pharm     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-29     Completed Date:  2013-09-24     Revised Date:  2014-11-17    
Medline Journal Info:
Nlm Unique ID:  9605854     Medline TA:  J Manag Care Pharm     Country:  United States    
Other Details:
Languages:  eng     Pagination:  218-27     Citation Subset:  IM    
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MeSH Terms
Continuity of Patient Care*
Depressive Disorder, Major / drug therapy*
Middle Aged
Outcome Assessment (Health Care) / methods*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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