| Assessment of Coronary Flow Parameters by Transesophageal Echocardiography in Patients with Isolated Coronary Artery Ectasia: Effect of Intravenous Nitroglycerin. | |
| | |
MedLine Citation:
|
PMID: 20456477 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Background: We sought to assess coronary flow parameters in patients with isolated coronary artery ectasia (CAE) as compared to subjects with normal coronaries. Methods: Consecutively, we enrolled 30 patients with ectasia of the left anterior descending (LAD) coronary artery (study group), and 10 subjects with normal coronaries (control group). All patients underwent transesophageal echocardiography to visualize the LAD. Spectral recordings of proximal LAD flow velocities were made and velocity time integrals were calculated. The diameter of the proximal LAD was measured and LAD blood flow was calculated. Nitroglycerin (0.3 mg) was administered intravenously and measurements were repeated 5 minutes later. Results: The mean age of the whole series was 48.6 +/- 8 years, 39 (97.5%) being males. A significantly higher baseline systolic, diastolic, and total coronary blood flow was found in the study group as compared to the control group (46.1 +/- 34.3 vs. 23.1 +/- 8.2, 123.9 +/- 73.3 vs. 68.1 +/- 21.6, 170.1 +/- 97.9 vs. 91.1 +/- 26.8 cm(3)/min, respectively, P < 0.05 for all). Within the study group, nitroglycerin administration caused a significant decrease in peak diastolic velocity; systolic, diastolic, and total velocity time integrals; and both diastolic and total coronary blood flow (P < 0.05 for all). Meanwhile, within the control group, nitroglycerin administration caused a significant increase in the total coronary blood flow (P < 0.05). Conclusions: Patients with CAE have higher resting coronary blood flow in comparison with subjects with normal coronaries. Intravenous nitroglycerin administration causes significant reduction of coronary blood flow in ectatic coronary arteries. (Echocardiography ****;**:1-7). |
| | |
Authors:
|
Tarek M K Abdeldayem; Ramzy El-Mawardy; M Khairy Abdel-Dayem; Mona Rayan; Ahmed El-Mahmoudy; Gamal Shawky; Wail Nammas |
Related Documents
:
|
9890407 - Effect of nitroglycerin and nicorandil on regional poststenotic quantitative coronary b... 3401267 - Cardiovascular effects of a new 1,5-benzothiazepine calcium antagonist in anesthetized ... 10409287 - Myocardial blood flow and coronary reserve in chronically anemic fetal lambs. 1878197 - The effect of distension of the urinary bladder on coronary blood flow in anesthetized ... 9890407 - Effect of nitroglycerin and nicorandil on regional poststenotic quantitative coronary b... 20586597 - Caudwell xtreme everest expedition. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2010-4-23 |
Journal Detail:
|
Title: Echocardiography (Mount Kisco, N.Y.) Volume: - ISSN: 1540-8175 ISO Abbreviation: - Publication Date: 2010 Apr |
Date Detail:
|
Created Date: 2010-5-11 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8511187 Medline TA: Echocardiography Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Cardiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Potential Faces of Patent Foramen Ovale (PFO PFO).
Next Document: Telmisartan improves morphologic and functional changes in both left ventricular myocardium and caro...