Document Detail

Assessment of Cardiac Function in Monochorionic Diamniotic Twin Pregnancies with Twin-to-Twin Transfusion Syndrome Before and After Fetoscopic Laser Photocoagulation Using Speckle Tracking.
MedLine Citation:
PMID:  22623131     Owner:  NLM     Status:  Publisher    
Purpose: To assess cardiac function with Speckle tracking in fetuses with twin-to-twin transfusion syndrome (TTTS) before and after laser therapy. Materials and Methods: A prospective case control study was conducted on 11 monochorionic diamniotic twin pairs with TTTS. Based on normal curves derived from healthy controls, global systolic longitudinal myocardial velocity, strain and strain rate values were transformed to z-scores. Results: Right and left ventricular systolic global strain (-27.45 % and -22.41 %) and strain rate (-4.13/sec and -3.27/sec) were reduced in recipients compared with normal values and all parameters tended to decrease even more after treatment (RV and LV: strain -23.79 % and -20.21 %; strain rate: -3.67/sec and -2.87/sec). The corresponding measurements in donor fetuses revealed no statistical difference compared to reference values. Conclusion: The global systolic myocardial function of donor twins before and after laser therapy was in the normal ranges. In contrast, recipient twins exhibited global cardiac dysfunction with decreased pre- and postoperative strain and strain rate. Speckle tracking can identify compromised ventricular myocardial function in fetuses with TTTS.
A Willruth; A Geipel; C Berg; R Fimmers; U Gembruch
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-23
Journal Detail:
Title:  Ultraschall in der Medizin (Stuttgart, Germany : 1980)     Volume:  -     ISSN:  1438-8782     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8303585     Medline TA:  Ultraschall Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Deparment of Obstetrics and Prenatal Medicine, University Hospital, Bonn.
Vernacular Title:
Beurteilung der kardialen Funktion bei monochorialen diamnioten Gemini mit feto-fetalem Transfusionssyndrom vor und nach Lasertherapie mittels "Speckle-Tracking"-Technik.
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