| Assessment of Atrial Conduction Abnormalities in Patients with Hypertrophic Cardiomyopathy Before and One Year after Alcohol Septal Ablation. | |
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MedLine Citation:
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PMID: 23235112 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objectives: Intra- and interatrial electromechanical delay (AEMD) can be used to evaluate the development of atrial fibrillation (AF). Percutaneous transluminal septal myocardial ablation (PTSMA) is an alternative therapy for patients with hypertrophic obstructive cardiomyopathy (HOCM) that results in sustained improvements in atrial structure and function. We investigated the effects of PTSMA on the intra- and inter-AEMD of HOCM patients using tissue Doppler imaging. Methods: Conventional echocardiographic and AEMD parameters were obtained in 25 healthy controls and 31 HOCM patients before and 1 year after septal ablation procedures. Results: Compared with the healthy controls, the left atrial volumes indexed by body surface area (LAVI) and the intra- and inter-AEMD were significantly higher in the HOCM patients. At 1 year after PTSMA, the LAVI was decreased (37.2 ± 11.4 to 27.0 ± 8.5 ml/m(2), p < 0.001). The intra- and inter-AEMD were also significantly decreased (22.7 ± 9.2 to 16.6 ± 7.7 ms, p < 0.001 and 37.0 ± 8.4 to 26.6 ± 8.0 ms, p < 0.001, respectively). These changes correlated well with the reductions in LAVI (r = 0.83, p < 0.001; r = 0.66, p < 0.001). Conclusions: Both the intra- and inter-AEMD were significantly prolonged in the HOCM patients. PTSMA can improve the prolonged and inhomogeneous propagation of sinus impulses in atria. |
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Authors:
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Shi Chen; Jiansong Yuan; Jiafen Zhang; Shubin Qiao; Fujian Duan; Xiuzhang Lv; Fenghuan Hu; Weixian Yang; Yuejin Yang |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-07 |
Journal Detail:
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Title: Cardiology Volume: 123 ISSN: 1421-9751 ISO Abbreviation: Cardiology Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-12-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1266406 Medline TA: Cardiology Country: - |
Other Details:
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Languages: ENG Pagination: 254-260 Citation Subset: - |
Copyright Information:
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Copyright © 2012 S. Karger AG, Basel. |
Affiliation:
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Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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