| Assessment of the AmnioStat-FLM immunoagglutination test for phosphatidylglycerol in amniotic fluid. | |
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MedLine Citation:
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PMID: 3719984 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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One hundred and eight amniotic fluids were assayed by the AmnioStat-FLM (A-FLM) immunological agglutination test for phosphatidylglycerol (PG) and simultaneously measured enzymatically for PG content. Of 52 amniotic fluids found to be PG negative by the A-FLM method, all had enzymatic PG concentrations less than or equal to 1.5 mumol/l. Conversely, of 56 amniotic fluids judged to be either PG positive or weak positive, all but five had enzymatic PG concentrations greater than 1.5 mumol/l. The sensitivity of the A-FLM assay employed clinically for predicting foetal lung maturity was 89% and the specificity was 100%. The overall predictive accuracy of the test could be improved by providing controls at lower, more appropriate PG concentrations. Ninety-one fluids analysed by the A-FLM kit were subsequently tested for the presence of PG by two-dimensional thin-layer chromatography (2D TLC). A 94%-concordance between the methods was found. |
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Authors:
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J Farquharson; E C Jamieson; E Berry; R Buchanan; R W Logan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinica chimica acta; international journal of clinical chemistry Volume: 156 ISSN: 0009-8981 ISO Abbreviation: Clin. Chim. Acta Publication Date: 1986 May |
Date Detail:
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Created Date: 1986-07-25 Completed Date: 1986-07-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 1302422 Medline TA: Clin Chim Acta Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 271-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Agglutination Tests
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instrumentation Amniotic Fluid / analysis* Chromatography, Thin Layer Female Fetal Organ Maturity Gestational Age Humans Lung / embryology Phosphatidylglycerols / analysis* Pregnancy |
| Chemical | |
Reg. No./Substance:
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0/Phosphatidylglycerols |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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