Document Detail

Assessing total body and extracellular water from bioelectrical response spectroscopy.
MedLine Citation:
PMID:  9049756     Owner:  NLM     Status:  MEDLINE    
We developed and validated assessments for total body water (TBW) and extracellular water (ECW) by using two resistance values of a new electric circuit model (CM) (two resistors; a capacitor and an inductor) with or without body mass. Fluid shifts occurring after 40 min of supine rest did not increase the validity of either estimate. CM estimates were valid; r = 0.941 to 0.969, low SE of estimates of 1.15-2.28 kg, nonsignificant mean differences (CM - dilution; %delta = -0.4 to 1.3%) that were close to the expected measurement errors for TBW (+/- 1%) and ECW (+/- 5%), and Bland-Altman pairwise comparisons that showed equivalence between methods. The CM estimates of TBW and ECW had marginally better validity than the previously published bioimpedance models. The advantage of the CM model is its assessments of multiple fluid spaces and that it does not require gender-specific equations. We conclude that CM estimate of TBW is acceptable, whereas further validation is needed before the ECW estimate should be used in a clinical or research setting.
S F Siconolfi; R J Gretebeck; W W Wong; R A Pietrzyk; S S Suire
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  82     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-06-05     Completed Date:  1997-06-05     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  704-10     Citation Subset:  IM; S    
Exercise Physiology Laboratory, National Aeronautics and Space Administration, Johnson Space Center, Houston 77058, USA.
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MeSH Terms
Body Water / physiology*
Electric Impedance*
Mass Spectrometry
S F Siconolfi / JSC

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