| Assessing the role of hydration in delirium at the end of life. | |
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MedLine Citation:
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PMID: 21532351 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE OF REVIEW: Delirium is the most frequent neuropsychiatric disorder that affects the advanced cancer population who are receiving palliative care. There is limited evidence and much debate about the role of hydration in delirium management at the end of life. The purpose of this article is to review the literature on delirium management with regards to pharmacological management and hydration. RECENT FINDINGS: Pharmacological management is the first line of treatment for delirium, whereby antipsychotics are the medication of choice. However, they have not been approved by the United States Food and Drug Administration for delirium management as there is insufficient evidence supporting their use. Hydration is a believed to be a key component of delirium reversibility; yet there are conflicting results on its efficacy as an intervention for delirium management. As there are few studies of good methodological quality on the topic and large variations in practice, the effectiveness of hydration as an alternative management option for delirium is unclear. SUMMARY: More work is required to assess the role of hydration in delirium at the end of life. Given the lack of evidence-based research on hydration, more randomized clinical trials are needed to elucidate the effects of hydration as a delirium intervention. |
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Authors:
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Chrissi Galanakis; Nancy E Mayo; Bruno Gagnon |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current opinion in supportive and palliative care Volume: 5 ISSN: 1751-4266 ISO Abbreviation: Curr Opin Support Palliat Care Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-05-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101297402 Medline TA: Curr Opin Support Palliat Care Country: United States |
Other Details:
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Languages: eng Pagination: 169-73 Citation Subset: IM |
Affiliation:
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aDepartment of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Canada bDivision of Clinical Epidemiology, McGill University Health Centre, Canada cDepartment of Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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