Document Detail


Assessing the reproductive competence of individual embryos: a proposal for the validation of new "-omics" technologies.
MedLine Citation:
PMID:  20460188     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rapid technological advances now provide the tools needed to evaluate the molecular genetics, proteomics, and microenvironment of an individual embryo in an effort to predict its reproductive competence. Rigorous criteria for accepting any test as a validated marker of embryonic reproductive competence should be established, and practitioners should be cautious about applying these tests clinically before the availability of comprehensive and convincing evidence.
Authors:
Richard T Scott; Nathan R Treff
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2010-05-11
Journal Detail:
Title:  Fertility and sterility     Volume:  94     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-30     Completed Date:  2010-09-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  791-4     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Affiliation:
Reproductive Medicine Associates of New Jersey, Morristown, New Jersey 07962, USA. rscott@rmanj.com
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MeSH Terms
Descriptor/Qualifier:
Embryo, Mammalian / cytology*,  physiology*
Embryonic Development / physiology
Genomics / methods*,  standards
Humans
Proteomics / methods*,  standards
Quality Control
Reproduction / physiology
Validation Studies as Topic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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