Document Detail


Assessing prescriptions for statins in ambulatory diabetic patients in the United States: a national, cross-sectional study.
MedLine Citation:
PMID:  19108804     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Diabetes mellitus affects >20 million people in the United States each year, and >4000 new cases are diagnosed daily. OBJECTIVE: This study assessed the prescription of statin medications in the ambulatory setting in US diabetic patients. METHODS: We used data from the 2002 through 2004 National Ambulatory Medical Care Survey and National Hospital Ambulatory Medical Care Survey. All ambulatory medical visits associated with a diabetes diagnosis by the International Classification of Diseases, Ninth Revision, Clinical Modification were included. Prescriptions for statin medications were determined by searching each ambulatory visit for relevant drug names (trade and generic). Demographic characteristics were assessed, including survey year, sex, age group, race, ethnicity, payment type, region of the country, and physician's specialty and degree. Analyses used sample weights to calculate national estimates. RESULTS: From 2002 to 2004, 10,046 (unweighted) ambulatory visits were made by diabetic patients, representing a weighted national estimate of approximately 153 million visits. A statin prescription was associated with 21.1% of all diabetic visits and 14.1% of those without a hyperlipidemia-related diagnosis. Diabetic men were more likely than diabetic women to be given a prescription for a statin (odds ratio [OR], 1.38; 95% CI, 1.09-1.73). Compared with diabetic patients treated in 2002, those treated in 2003 and 2004 were more likely to be prescribed statin therapy (2003 OR, 1.51; 95% CI, 1.02-2.24; 2004 OR, 1.48; 95% CI, 1.03-2.15). Compared with diabetic patients aged 45 to 64 years, those in younger age groups were less likely to be given a statin prescription (1-24 years OR, 0.10; 95% CI, 0.01-0.84; 25-44 years OR, 0.48; 95% CI, 0.31-0.74), and those aged 65 to 74 years were more likely to be given a statin (OR, 1.38; 95% CI, 1.01-1.90). No differences were noted for diabetic patients aged > or = 75 years. CONCLUSIONS: From 2002 through 2004, <25% of the ambulatory medical visits by diabetic patients in the United States were associated with a statin prescription. Male sex and age up to 75 years had an increased association with statin prescription. Additional study is anticipated to assess changes in statin use in diabetic patients in the United States as updated treatment guidelines are released.
Authors:
Larry W Segars; Amanda R Lea
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical therapeutics     Volume:  30     ISSN:  0149-2918     ISO Abbreviation:  Clin Ther     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-12-25     Completed Date:  2009-02-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7706726     Medline TA:  Clin Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2159-66     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, Kansas City University of Medicine and Biosciences, Kansas City, Missouri 64106, USA. lsegars@kcumb.edu
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MeSH Terms
Descriptor/Qualifier:
Ambulatory Care / methods,  statistics & numerical data
Cross-Sectional Studies
Delivery of Health Care / statistics & numerical data
Diabetes Mellitus / drug therapy*,  ethnology
Drug Prescriptions / statistics & numerical data*
Drugs, Generic / therapeutic use
European Continental Ancestry Group / statistics & numerical data
Female
Hispanic Americans / statistics & numerical data
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
Male
Odds Ratio
Outpatients / statistics & numerical data
Physician's Practice Patterns
Quality of Health Care / statistics & numerical data
Sex Factors
United States / epidemiology
Chemical
Reg. No./Substance:
0/Drugs, Generic; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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