Document Detail

Assessing and predicting successful tube placement outcomes in ALS patients.
MedLine Citation:
PMID:  19714540     Owner:  NLM     Status:  MEDLINE    
This study reviews feeding tube placement outcomes in 69 ALS outpatients seen at an outpatient interdisciplinary ALS clinic in British Columbia, Canada. The objective was to determine at which point the risks outweigh the benefits of tube placement by reviewing outcomes against parameters of respiratory function, nutritional status and speech and swallowing deterioration. The study was a retrospective review of tube placements between January 2000 and 2005, analysing data on respiratory function (forced vital capacity and respiratory status), weight change from usual body weight (UBW) and speech/swallowing deterioration using ALS Severity Score ratings (Hillel et al., 1989) at time of tube placement. Results show a statistically significant association between nutritional status and successful tube placement outcomes (p=0.003), and none between respiratory status, speech/swallowing variables, or number of deteriorated variables in each patient. Study findings were impacted by lack of available respiratory data. The only study variable that predicted successful tube placement outcome was a body weight greater than or equal to 74% UBW at time of tube placement. In the absence of access to respiratory testing, the relatively simple assessment of weight may assist patients and caregivers in appropriate decisions around tube placement.
Kathleen Beggs; Marcia Choi; Andrew Travlos
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases     Volume:  11     ISSN:  1471-180X     ISO Abbreviation:  Amyotroph Lateral Scler     Publication Date:  2010  
Date Detail:
Created Date:  2010-05-04     Completed Date:  2010-08-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101283386     Medline TA:  Amyotroph Lateral Scler     Country:  England    
Other Details:
Languages:  eng     Pagination:  203-6     Citation Subset:  IM    
Vancouver Coastal Health ALS Centre, Canada. <>
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MeSH Terms
Amyotrophic Lateral Sclerosis / epidemiology*,  therapy*
Body Weight
Deglutition Disorders / diagnosis,  epidemiology
Disease Progression
Dysarthria / diagnosis,  epidemiology
Enteral Nutrition / statistics & numerical data*
Gastric Bypass / statistics & numerical data
Gastrostomy / statistics & numerical data
Middle Aged
Nutritional Status
Outcome Assessment (Health Care)
Outpatient Clinics, Hospital / statistics & numerical data*
Predictive Value of Tests
Respiratory Insufficiency / diagnosis,  epidemiology
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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