| Assessing health risks of inhaled nanomaterials: development of pulmonary bioassay hazard studies. | |
MedLine Citation:
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PMID: 20665009 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This brief discussion provides an overview of current concepts and perceptions regarding the pulmonary toxicity of ultrafine or nanoparticles. These aspects include, but are not limited to comparisons of fine particle vs. ultrafine particle effects and the unique response of pulmonary effects in rats vs. other rodent species, particularly at particle overload concentrations. In the final section, two studies are described which demonstrate that particle size is not the most significant particulate factor in producing exposure-related pulmonary effects. |
Authors:
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David B Warheit |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-07-28 |
Journal Detail:
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Title: Analytical and bioanalytical chemistry Volume: 398 ISSN: 1618-2650 ISO Abbreviation: Anal Bioanal Chem Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-15 Completed Date: 2011-01-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101134327 Medline TA: Anal Bioanal Chem Country: Germany |
Other Details:
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Languages: eng Pagination: 607-12 Citation Subset: IM |
Affiliation:
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DuPont Haskell Global Centers for Health and Environmental Sciences, 1090 Elkton Road, P.O. Box 50, Newark, Delaware 19714-0050, USA. David.B.Warheit@USA.dupont.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Humans Lung / pathology* Nanostructures / adverse effects, chemistry, toxicity* Particle Size Risk Assessment Toxicology / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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