Document Detail


Assessing the accuracy and precision of musculoskeletal motion tracking using cine-PC MRI on a 3.0T platform.
MedLine Citation:
PMID:  20863502     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The rising cost of musculoskeletal pathology, disease, and injury creates a pressing need for accurate and reliable methods to quantify 3D musculoskeletal motion, fostering a renewed interest in this area over the past few years. To date, cine-phase contrast (PC) MRI remains the only technique capable of non-invasively tracking in vivo 3D musculoskeletal motion during volitional activity, but current scan times are long on the 1.5T MR platform (∼ 2.5 min or 75 movement cycles). With the clinical availability of higher field strength magnets (3.0T) that have increased signal-to-noise ratios, it is likely that scan times can be reduced while improving accuracy. Therefore, the purpose of this study is to validate cine-PC MRI on a 3.0T platform, in terms of accuracy, precision, and subject-repeatability, and to determine if scan time could be minimized. On the 3.0T platform it is possible to limit scan time to 2 min, with sub-millimeter accuracy (<0.33 mm/0.97°), excellent technique precision (<0.18°), and strong subject-repeatability (<0.73 mm/1.10°). This represents reduction in imaging time by 25% (42 s), a 50% improvement in accuracy, and a 72% improvement in technique precision over the original 1.5T platform. Scan time can be reduced to 1 min (30 movement cycles), but the improvements in accuracy are not as large.
Authors:
Abrahm J Behnam; Daniel A Herzka; Frances T Sheehan
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Intramural; Validation Studies     Date:  2010-09-21
Journal Detail:
Title:  Journal of biomechanics     Volume:  44     ISSN:  1873-2380     ISO Abbreviation:  J Biomech     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-17     Completed Date:  2011-04-12     Revised Date:  2012-01-05    
Medline Journal Info:
Nlm Unique ID:  0157375     Medline TA:  J Biomech     Country:  United States    
Other Details:
Languages:  eng     Pagination:  193-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Rehabilitation Medicine Department, National Institutes of Health, Building 10 CRC RM 1-1469, 10 Center Drive MSC 1604, Bethesda, MD 20892-1604, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biomechanics
Female
Humans
Imaging, Three-Dimensional
Knee Joint / physiology
Magnetic Resonance Imaging, Cine / instrumentation*,  methods*
Male
Movement / physiology*
Musculoskeletal Physiological Processes
Phantoms, Imaging*
Reproducibility of Results
Young Adult
Grant Support
ID/Acronym/Agency:
Z99 CL999999/CL/CLC NIH HHS; ZIA CL060062-07/CL/CLC NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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