Document Detail


Assessing the Impact of Osteoporosis on the Burden of Hip Fractures.
MedLine Citation:
PMID:  23135744     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The aim of the study was to determine the number of hip fractures within defined countries for 2010 and the proportion attributable to osteoporosis. The number of incident hip fractures in one year in countries for which data were available was calculated from the population demography in 2010 and the age- and sex-specific risk of hip fracture. The number of hip fractures attributed to osteoporosis was computed as the number of hip fractures that would be saved assuming that no individual could have a femoral neck T-score of less than -2.5 SD (i.e., the lowest attainable T-score was that at the threshold of osteoporosis (=-2.5 SD). The total number of new hip fractures for 58 countries was 2.32 million (741,005 in men and 1,578,809 in women) with a female-to-male ratio of 2.13. Of these 1,159,727 (50 %) would be saved if bone mineral density in individuals with osteoporosis were set at a T-score of -2.5 SD. The majority (83 %) of these "prevented" hip fractures were found in men and women at the age of 70 years or more. The 58 countries assessed accounted for 83.5 % of the world population aged 50 years or more. Extrapolation to the world population using age- and sex-specific rates gave an estimated number of hip fractures of approximately 2.7 million in 2010, of which 1,364,717 were preventable with the avoidance of osteoporosis (264,162 in men and 1,100,555 in women). We conclude that osteoporosis accounts for approximately half of all hip fractures. Strategies to prevent osteoporosis could save up to 50 % of all hip fractures.
Authors:
Anders Odén; Eugene V McCloskey; Helena Johansson; John A Kanis
Related Documents :
11108214 - Relationship between fracture toughness and impact strength of acrylic bone cement.
17259414 - Cemented versus hydroxyapatite fixation of the femoral component of the freeman-samuels...
1940924 - Distal femoral plug migration with cement pressurization in revision surgery and a simp...
3999714 - A model of tension and compression cracks with cohesive zone at a bone-cement interface.
7092084 - The significance of distal arteriovenous shunting on skin flap survival an experimental...
24642054 - Viability and long-term survival of short-segment posterior fixation in thoracolumbar b...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-8
Journal Detail:
Title:  Calcified tissue international     Volume:  -     ISSN:  1432-0827     ISO Abbreviation:  Calcif. Tissue Int.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7905481     Medline TA:  Calcif Tissue Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hill Road, Sheffield, S10 2RX, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Segmented Flow Reactors for Nanocrystal Synthesis.
Next Document:  Trees Assembling Mann-Whitney approach for detecting genome-wide joint association among low-margina...