Document Detail


Assessing chronological aging in Saccharomyces cerevisiae.
MedLine Citation:
PMID:  23296677     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Saccharomyces cerevisiae is one of the most studied model organisms for the identification of genes and mechanisms that affect aging. The chronological lifespan (CLS) assay, which monitors the survival of a non-dividing population, is one of the two methods to study aging in yeast. To eliminate potential artifacts and identify genes and signaling pathways that may also affect aging in higher eukaryotes, it is important to determine CLS by multiple methods. Here, we describe these methods as well as the assays to study macromolecular damage during aging in yeast, with a focus on genomic instability.
Authors:
Jia Hu; Min Wei; Mario G Mirisola; Valter D Longo
Related Documents :
18586987 - A one-day census of acute psychiatric inpatient facilities in italy: findings from the ...
24259827 - Changes in acromion and scapular position after short-term overhead work.
22940797 - Visual acuity and factors influencing automobile driving status in 1,000 patients age 6...
24217457 - Psychometric properties of the cannabis abuse screening test in hungarian samples of ad...
20674197 - Antenatal antecedents of a small head circumference at age 24-months post-term equivale...
16860327 - Determinants of carotid intima-medial thickness in an urban australian aboriginal popul...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  965     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2013  
Date Detail:
Created Date:  2013-01-08     Completed Date:  2013-06-13     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  463-72     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cell Nucleus / genetics
Culture Media / chemistry
DNA, Fungal / genetics
Genomic Instability
Mutation Rate
Saccharomyces cerevisiae / cytology,  genetics*,  growth & development*
Time Factors
Water / chemistry
Grant Support
ID/Acronym/Agency:
R01 AG020642/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
0/Culture Media; 0/DNA, Fungal; 059QF0KO0R/Water
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Assessing Organismal Aging in the Filamentous Fungus Podospora anserina.
Next Document:  Assessing Aging and Senescent Decline in Caenorhabditis elegans: Cohort Survival Analysis.