Document Detail

Assessing Cell Size and Cell Cycle Regulation in Cells with Altered TOR Activity.
MedLine Citation:
PMID:  22125068     Owner:  NLM     Status:  In-Data-Review    
Target of rapamycin (TOR) regulates the growth of cells and organisms. Numerous growth-promoting and growth-arresting pathways converge on TOR; TOR acts as an important hub, balancing the pro- and anti-growth signals within a cell. Since it regulates growth at the cellular level, cell size can be used as an indirect readout of TOR activity. Here, we describe methods used to analyze cell size in cell culture and in the Drosophila wing.
Megan Cully; Julian Downward
Related Documents :
10322008 - Deletion of new covalently linked cell wall glycoproteins alters the electrophoretic mo...
15937228 - Lipid transfer proteins enhance cell wall extension in tobacco.
18694928 - Assembly of the yeast cell wall. crh1p and crh2p act as transglycosylases in vivo and i...
1396728 - Effects of fluconazole on the sterol and carbohydrate composition of four species of ca...
2996958 - Appearance of nerve growth factor receptors on cultured neural crest cells.
1429198 - Potentiation of the vincristine effect on p388 mouse leukemia cells by a newly synthesi...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  821     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2012  
Date Detail:
Created Date:  2011-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  227-37     Citation Subset:  IM    
Signal Transduction Laboratory, Cancer Research UK London Research Institute, London, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Immunohistochemical Analysis of mTOR Activity in Tissues.
Next Document:  Quantitative Visualization of Autophagy Induction by mTOR Inhibitors.