Document Detail


Assembling complex I with ACAD9.
MedLine Citation:
PMID:  20816087     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Acyl-Co dehydrogenase 9 (ACAD9) was thought to play a role in fatty acid oxidation. Nouws et al. (2010) reveal a novel and essential role for this enzyme in mitochondrial complex I assembly. A mutation in ACAD9 causes an isolated complex I deficiency in a subset of patients with mitochondrial disease.
Authors:
Immo E Scheffler
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cell metabolism     Volume:  12     ISSN:  1932-7420     ISO Abbreviation:  Cell Metab.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-06     Completed Date:  2010-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101233170     Medline TA:  Cell Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  211-2     Citation Subset:  -    
Copyright Information:
2010 Elsevier Inc. All rights reserved.
Affiliation:
University of California, San Diego, La Jolla, 92093-0322, USA. ischeffler@ucsd.edu
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Comment On:
Cell Metab. 2010 Sep 8;12(3):283-94   [PMID:  20816094 ]

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