| Aspirin resistance in cardiovascular disease: a review. | |
| | |
MedLine Citation:
|
PMID: 15079767 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Aspirin is effective at reducing the cardiovascular event rate in defined patient groups. The introduction of antiplatelet therapies other than aspirin and the concept of aspirin resistance have led to critical reappraisal of current treatment. This review aims to clarify the evidence for aspirin resistance in patients with atherosclerosis. METHODS: Medline search was performed to identify publications concerned with antiplatelet effects of aspirin and failure of aspirin therapy. Manual cross referencing was also performed. RESULTS AND CONCLUSION: Wide variations in the rate of aspirin resistance (5.5-75%) have been reported. The lack of consensus on an appropriate definition and the number of different tests used to investigate aspirin resistance needs to be addressed. There are few studies where the primary aim was to document aspirin resistance or aspirin non-response. Further work should aim to investigate if aspirin resistance is clinically important and, if it is, what treatments may be beneficial to the at risk patient. |
| | |
Authors:
|
S Wong; M Appleberg; C M Ward; D R Lewis |
Related Documents
:
|
11276267 - Slip resistance of industrial floor surfaces: development of an elastomer suited to in-... 22322527 - Biodegradation of semiconductor volatile organic compounds by four novel bacterial stra... 22562107 - Influence of biotic and abiotic factors on the allelopathic activity of the cyanobacter... 8813567 - Vasoconstriction by endothelin-1 in resistance and conduit portions of isolated human m... 15264987 - An update on the medical management of listeriosis. 12440197 - Multiplex pcr for detection of stx genes of escherichia coli. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery Volume: 27 ISSN: 1078-5884 ISO Abbreviation: Eur J Vasc Endovasc Surg Publication Date: 2004 May |
Date Detail:
|
Created Date: 2004-04-13 Completed Date: 2004-06-10 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 9512728 Medline TA: Eur J Vasc Endovasc Surg Country: England |
Other Details:
|
Languages: eng Pagination: 456-65 Citation Subset: IM |
Affiliation:
|
Department of Vascular Surgery, The Royal North Shore Hospital, St Leonard's, Sydney, NSW 2065, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Arteriosclerosis
/
prevention & control* Aspirin / administration & dosage, pharmacology*, therapeutic use Drug Resistance Humans Platelet Aggregation Inhibitors / administration & dosage, pharmacology*, therapeutic use |
| Chemical | |
Reg. No./Substance:
|
0/Platelet Aggregation Inhibitors; 50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Hydroxychloroquine cardiotoxicity in systemic lupus erythematosus: a report of 2 cases and review of...
Next Document: 25 years of laser assisted vascular anastomosis (LAVA): what have we learned?