| Aspirin and congenital malformations. | |
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MedLine Citation:
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PMID: 59014 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a cohort of 50 282 gravidas and their offspring in the U.S.A., malformation rates were similar in the children of 35 418 women not exposed to aspirin, 9736 with intermediate exposure, and 5128 women heavily exposed during the first four lunar months of pregnancy. After controlling a wide range of potential confounding factors using multi-variate analysis, the observed and expected numbers for a variety of malformation categories were similar in all three comparison groups. The data suggest that aspirin is not teratogenic. |
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Authors:
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D Slone; V Siskind; O P Heinonen; R R Monson; D W Kaufman; S Shapiro |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Lancet Volume: 1 ISSN: 0140-6736 ISO Abbreviation: Lancet Publication Date: 1976 Jun |
Date Detail:
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Created Date: 1976-08-23 Completed Date: 1976-08-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985213R Medline TA: Lancet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1373-5 Citation Subset: AIM; IM; J |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Drug-Induced
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etiology* Abnormalities, Multiple / chemically induced Aspirin / administration & dosage, adverse effects* Birth Weight / drug effects Female Humans Infant, Newborn Infant, Newborn, Diseases / mortality Maternal-Fetal Exchange Pregnancy Smoking / complications Time Factors |
| Chemical | |
Reg. No./Substance:
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50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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