| Aspirin-associated intracerebral hemorrhage in a patient with CADASIL. | |
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MedLine Citation:
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PMID: 18207319 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary disease characterized by ischemic stroke, cognitive impairment, migraine and neuropsychological deficit. Although intracerebral hemorrhage (ICH) has been described in patients with CADASIL, the cause of such ICH is still unknown. We present a 39-year-old man with CADASIL who had two years history of untreated hypertension. In this patient, acute ICH developed only two weeks after the initiation of aspirin. Brain images demonstrated a 3cmx3cm hyperacute ICH in the left temporal lobe at the site of previous old hemorrhage. The presence of cerebral microbleed and use of antithrombotics may be associated with development of ICH in patients with CADASIL. |
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Authors:
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Jung-Hwan Oh; Jung Seok Lee; Sa-Yoon Kang; Ji-Hoon Kang; Jay Chol Choi |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-01-22 |
Journal Detail:
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Title: Clinical neurology and neurosurgery Volume: 110 ISSN: 0303-8467 ISO Abbreviation: Clin Neurol Neurosurg Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-04-04 Completed Date: 2008-07-15 Revised Date: 2009-10-14 |
Medline Journal Info:
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Nlm Unique ID: 7502039 Medline TA: Clin Neurol Neurosurg Country: Netherlands |
Other Details:
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Languages: eng Pagination: 384-6 Citation Subset: IM |
Affiliation:
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Department of Neurology, Cheju National University School of Medicine, Jeju, Republic of Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Aspirin / administration & dosage, adverse effects* CADASIL / complications*, diagnosis Cerebral Hemorrhage / chemically induced*, diagnosis Diffusion Magnetic Resonance Imaging Follow-Up Studies Humans Male Platelet Aggregation Inhibitors / administration & dosage, adverse effects* Risk Factors Stroke / prevention & control Temporal Lobe / pathology Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Platelet Aggregation Inhibitors; 50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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