Document Detail


Aspiration biopsy of testis: another method for histologic examination.
MedLine Citation:
PMID:  6745461     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The most important method for evaluating the pathogenesis of male infertility is open testicular biopsy. Herein we describe a method of aspiration biopsy of testis for histologic examination. Sexually mature dogs and rats treated with chemotherapeutic agents and ionizing radiation were followed with periodic testicular aspiration biopsy during and after treatment. The histologic findings from the aspiration biopsy compare with the results of routine histologic examinations in assessing spermatogenetic activity and delineating pathologic changes. The puncture in the experimental animals was performed under general anesthesia. In human patients testicular biopsy could be done under local anesthesia in an outpatient clinic. The procedure would be less painful, minimally invasive, and more cost-effective.
Authors:
U O Nseyo; L S Englander; R P Huben; J E Pontes
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  42     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-09-10     Completed Date:  1984-09-10     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  281-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Biopsy, Needle / methods
Cyclophosphamide / pharmacology
Dogs
Male
Rats
Rats, Inbred Strains
Spermatogenesis
Testis / cytology*,  drug effects
Chemical
Reg. No./Substance:
50-18-0/Cyclophosphamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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