Document Detail

Aspiration thrombectomy with primary PCI for STEMI: review of the data and current guidelines.
MedLine Citation:
PMID:  20947929     Owner:  NLM     Status:  In-Process    
The presence of visible thrombus at the time of primary PCI for STEMI is associated with poor procedural and clinical outcomes. Aspiration thrombectomy has been used with primary PCI in an attempt to improve these outcomes. The TAPAS (Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction) Trial found that aspiration improved myocardial blush scores and ST-segment resolution (STR), and also was associated with lower mortality at 1 year. Four meta-analyses have shown improved measures of myocardial reperfusion (TIMI flow, myocardial blush, and STR) and improved procedural outcomes (reduced no-reflow and distal embolization), and three of four trials have shown reduced mortality. Aspiration thrombectomy has received a Class IIa indication with primary PCI in the recent ACC/AHA and ESC Guidelines. Unanswered questions include whether there is truly a mortality benefit with aspiration, which subgroups may and may not benefit from aspiration, and whether patients with large thrombus burden are better treated with mechanical thrombectomy.
Bruce R Brodie
Related Documents :
23812939 - International survey of t2* cardiovascular magnetic resonance in beta thalassemia major.
19850249 - Benefit of facilitated percutaneous coronary intervention in high-risk st-segment eleva...
17967609 - Ethnicity and socioeconomic status influence use of primary angioplasty in patients pre...
24975909 - Natriuretic peptides in heart failure with preserved ejection fraction.
18215599 - Treatment delay in patients undergoing primary percutaneous coronary intervention for s...
24831809 - Cardioprotective effects of the if current inhibition by ivabradine during cardiac dysf...
6858429 - Myocardial infarction, cardiac rupture, and coronary insufficiency in the industrialise...
12743659 - Percutaneous balloon angioplasty for the treatment of iliofemoral arterial stenosis res...
16092589 - Atypical presentation of eosinophilic endomyocardial disease.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  22     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2B-5B     Citation Subset:  IM    
LeBauer Cardiovascular Research Foundation, Greensboro, North Carolina, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Large cell neuroendocrine carcinoma of the ampulla of vater with adenocarcinoma and squamous cell ca...
Next Document:  Angiographic thrombus burden classification in patients with ST-segment elevation myocardial infarct...