Document Detail

Aspergillus pachymeningitis mimicking nasopharyngeal carcinoma.
MedLine Citation:
PMID:  20868533     Owner:  NLM     Status:  In-Process    
OBJECTIVES: We report a case of otogenic fungal pachymeningitis in a diabetic patient who presented with multiple cranial nerve palsies and nasopharyngeal swelling.
METHODS: We present a case report, we describe the investigations, management and clinical course of fungal pachymeningitis, and we present a review of the world literature on fungal and non-fungal pachymeningitis.
RESULTS: To our knowledge, this is the first report of fungal pachymeningitis with magnetic resonance imaging features suggestive of nasopharyngeal carcinoma. It is also the first reported case with aspergillus cultured from both a dural biopsy and the ear canal.
CONCLUSION: Fungal pachymeningitis is a rare condition which may present to otorhinolaryngologists. Its clinical and radiological findings can be confused with those of nasopharyngeal carcinoma; fungal pachymeningitis should thus be included in the differential diagnosis of nasopharyngeal carcinoma.
H S Chan; H Y Yuen; W K Ng; A C Vlantis; A T Ahuja; C F M Tong; C A van Hasselt
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Publication Detail:
Type:  Journal Article     Date:  2010-09-27
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  125     ISSN:  1748-5460     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  England    
Other Details:
Languages:  eng     Pagination:  103-7     Citation Subset:  AIM; IM    
Department of Otorhinolaryngology Head and Neck Surgery, The Chinese University of Hong Kong, China.
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