Document Detail

Aspergillus detection in bronchoscopically acquired material. Significance and interpretation.
MedLine Citation:
PMID:  11766098     Owner:  NLM     Status:  MEDLINE    
Pulmonary invasive aspergillosis is frequently difficult to diagnose. In particular, the value of the cultivation of Aspergillus and the Aspergillus galactomannan antigen detection (Pastorex) in bronchoscopically acquired material (bronchoalveolar lavage = BAL, bronchial lavage = BL) in the course of diagnosing this mycosis is viewed controversially. Between January 1996 and September 1999, we obtained 114 positive results in 100 bronchoscopically aquired specimens from a total of 69 patients. 59 of the 69 patients were immunosuppressed, 42 suffered from pulmonary aspergillosis and 38 suffered from invasive pulmonary aspergillosis. The positive prediction rate for a positive result with regard to pulmonary aspergillosis in bronchoscopically acquired material was approximately 61%. Cultivation of Aspergillus was more successful in BAL, and the Aspergillus antigen detection was more successful in BL.
H J Seyfarth; P Nenoff; J Winkler; R Krahl; U F Haustein; J Schauer
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Mycoses     Volume:  44     ISSN:  0933-7407     ISO Abbreviation:  Mycoses     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-12-18     Completed Date:  2002-02-28     Revised Date:  2007-02-09    
Medline Journal Info:
Nlm Unique ID:  8805008     Medline TA:  Mycoses     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  356-60     Citation Subset:  IM    
Medizinische Klinik I, Abteilung Pneumologie, Universität Leipzig, Germany.
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MeSH Terms
Antigens, Fungal / analysis
Aspergillosis / diagnosis,  microbiology*
Aspergillus / immunology,  isolation & purification*
Bronchoalveolar Lavage
Lung Diseases, Fungal / diagnosis,  microbiology*
Mannans / analysis
Retrospective Studies
Reg. No./Substance:
0/Antigens, Fungal; 0/Mannans; 11078-30-1/galactomannan

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