Document Detail


Aspergillus detection in bronchoscopically acquired material. Significance and interpretation.
MedLine Citation:
PMID:  11766098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pulmonary invasive aspergillosis is frequently difficult to diagnose. In particular, the value of the cultivation of Aspergillus and the Aspergillus galactomannan antigen detection (Pastorex) in bronchoscopically acquired material (bronchoalveolar lavage = BAL, bronchial lavage = BL) in the course of diagnosing this mycosis is viewed controversially. Between January 1996 and September 1999, we obtained 114 positive results in 100 bronchoscopically aquired specimens from a total of 69 patients. 59 of the 69 patients were immunosuppressed, 42 suffered from pulmonary aspergillosis and 38 suffered from invasive pulmonary aspergillosis. The positive prediction rate for a positive result with regard to pulmonary aspergillosis in bronchoscopically acquired material was approximately 61%. Cultivation of Aspergillus was more successful in BAL, and the Aspergillus antigen detection was more successful in BL.
Authors:
H J Seyfarth; P Nenoff; J Winkler; R Krahl; U F Haustein; J Schauer
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Mycoses     Volume:  44     ISSN:  0933-7407     ISO Abbreviation:  Mycoses     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-12-18     Completed Date:  2002-02-28     Revised Date:  2007-02-09    
Medline Journal Info:
Nlm Unique ID:  8805008     Medline TA:  Mycoses     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  356-60     Citation Subset:  IM    
Affiliation:
Medizinische Klinik I, Abteilung Pneumologie, Universität Leipzig, Germany.
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MeSH Terms
Descriptor/Qualifier:
Antigens, Fungal / analysis
Aspergillosis / diagnosis,  microbiology*
Aspergillus / immunology,  isolation & purification*
Bronchoalveolar Lavage
Humans
Lung Diseases, Fungal / diagnosis,  microbiology*
Mannans / analysis
Retrospective Studies
Chemical
Reg. No./Substance:
0/Antigens, Fungal; 0/Mannans; 11078-30-1/galactomannan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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