Document Detail


Aspects of the incidence of central nervous system malformations in Cologne 1971-1980.
MedLine Citation:
PMID:  3900549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Within the framework of a retrospective epidemiological investigation concerning the incidence of CNS-malformations in the city of Cologne during the period 1971-80, 76 749 hospital births assessed from records in six hospitals were considered. This represents 88% of all hospital births. The incidence varied between 0.79-1.80 with a mean of 1.37/1000 total births. This figure was primarily influenced by the values obtained from Spina bifida (0,59/1000). If the dates for the period 1961-70 are included, a marginal increment is exhibited (from 1.13 up to 1.37/1000) for the total occurrence of CNS-births, as opposed to a slight decrease for the Sb-group (0,65 down to 0.59/1000). A seasonal variation was not revealed for the total number of births. Contrary to worldwide literature, the male rates were significantly higher (113 : 100). The stillbirth-rate was 23,8% compared to 0,63% of total births, whereby hydrocephalus cases with 52% were heavily represented. A relationship between mother's age and incidence of occurrence was, as in the previous decade, not substantiated. Since the dates presented are obtained on the basis of hospital obstetrics records, it is unlikely that similar figures will arise in future studies, due to improved prenatal diagnosis (sonography and amniocentesis), which influence decisions relating to the possibilities of interruption of pregnancy.
Authors:
K Schüle
Related Documents :
7644439 - Prenatal diagnosis of autosomal recessive osteopetrosis, infantile type, by x-ray evalu...
10483549 - Successful pregnancy outcome in a woman with a gain-of-function mutation of the calcium...
20936639 - Confined placental mosaicism and pregnancy outcome: a distinction needs to be made betw...
17234369 - Early detection of cell-free fetal dna in maternal plasma.
7971759 - Prenatal diagnosis of sjögren-larsson syndrome using enzymatic methods.
264089 - Factors affecting the success of mid-trimester amniocentesis.
17348329 - Community-based survey of unwanted pregnancy in southwestern nigeria.
7936519 - The effect of indomethacin tocolysis on maternal coagulation status.
18155199 - Pregnancy after in vitro fertilization-intracytoplasmic sperm injection obtained with a...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Klinische Pädiatrie     Volume:  197     ISSN:  0300-8630     ISO Abbreviation:  Klin Padiatr     Publication Date:    1985 Jul-Aug
Date Detail:
Created Date:  1985-11-07     Completed Date:  1985-11-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0326144     Medline TA:  Klin Padiatr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  277-81     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anencephaly / epidemiology*
Cross-Sectional Studies
Encephalocele / epidemiology*
Germany, West
Humans
Hydrocephalus / epidemiology*
Infant, Newborn
Spina Bifida Occulta / epidemiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Conjunctival impression in the keratoconjunctivitis sicca syndrome
Next Document:  Non-immunologic hydrops fetalis--report of 14 cases and literature review