| Aspartate:2-oxoglutarate aminotransferase from Trichomonas vaginalis: comparison with pig heart cytoplasmic enzyme. | |
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MedLine Citation:
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PMID: 2876843 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aspartate:2-oxoglutarate aminotransferase from the protozoon Trichomonas vaginalis exists as a mixture of sub-forms of identical Mr and amino acid composition, and of similar catalytic properties. The amino acid composition closely resembles that of aspartate aminotransferase from prokaryotic and vertebrate sources. Some molecular and catalytic properties of the T. vaginalis aspartate aminotransferase are compared with those of the cytoplasmic pig heart enzyme. A major difference is in the ability of the trichomonal enzyme to transaminate aromatic amino acids and 2-oxo acids. A range of inhibitors have been used to compare the active-site regions of the T. vaginalis and cytoplasmic pig heart aspartate aminotransferases. |
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Authors:
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P N Lowe; A F Rowe |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Comparative biochemistry and physiology. B, Comparative biochemistry Volume: 85 ISSN: 0305-0491 ISO Abbreviation: Comp. Biochem. Physiol., B Publication Date: 1986 |
Date Detail:
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Created Date: 1986-12-17 Completed Date: 1986-12-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2984730R Medline TA: Comp Biochem Physiol B Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 93-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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analysis Animals Aspartate Aminotransferases / isolation & purification, metabolism* Cytoplasm / enzymology Kinetics Myocardium / enzymology* Species Specificity Swine / metabolism* Trichomonas vaginalis / enzymology* Tyrosine Transaminase / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.6.1.5/Tyrosine Transaminase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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