Document Detail

Aspartate-aminopeptidase activity during the estrous cycle and the pregnancy in rat brain and pituitary gland.
MedLine Citation:
PMID:  8223984     Owner:  NLM     Status:  MEDLINE    
The present report describes the activity of aspartate aminopeptidase, in 9 brain areas and in the pituitary gland, during the estrous cycle and several stages of pregnancy of the rat. The quantitation of the enzyme activity was performed by measuring the rate of hydrolysis of the chromogenic substrate Asp-beta-naphthylamide. Aspartate aminopeptidase activity, in the pituitary gland and in several limbic areas, was found to be greater in cyclic than in pregnant rats. However the enzyme activity did not change significantly during either the estrous cycle and pregnancy.
J M de Gandarias; J Irazusta; E Echevarria; L Casis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental and clinical endocrinology     Volume:  101     ISSN:  0232-7384     ISO Abbreviation:  Exp. Clin. Endocrinol.     Publication Date:  1993  
Date Detail:
Created Date:  1993-12-20     Completed Date:  1993-12-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8302802     Medline TA:  Exp Clin Endocrinol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  156-60     Citation Subset:  IM    
Department of Physiology, Medical School, University of the Basque Country, Bilbao, Spain.
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MeSH Terms
Aminopeptidases / metabolism*
Aspartic Acid / analogs & derivatives,  metabolism
Brain / enzymology*
Estrus / physiology*
Glutamyl Aminopeptidase
Pituitary Gland / enzymology*
Pregnancy, Animal / physiology*
Rats, Sprague-Dawley
Spectrometry, Fluorescence
Reg. No./Substance:
56-84-8/Aspartic Acid; 635-91-6/aspartic acid beta-naphthylamide; EC 3.4.11.-/Aminopeptidases; EC Aminopeptidase

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