Document Detail


Aspartame and dizziness: preliminary results of a prospective, nonblinded, prevalence and attempted cross-over study.
MedLine Citation:
PMID:  1443079     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aspartame is a low-calorie food sweetener recently approved by the FDA for general human consumption. One of us (AJG) treated a patient whose symptoms of episodic vertigo and continuous unsteadiness resolved upon ceasing aspartame intake. A literature review revealed that although dizziness has been associated with aspartame intake, no systematic study of the problem exists. As an initial attempt to ascertain the prevalence of aspartame-related dizziness in an otolaryngologic clinic, we elected to study prospectively all patients entering with the complaint of vertigo by means of a standardized questionnaire. Those patients determined to consume aspartame were further studied in a nonblinded manner to see if aspartame intake could be correlated to symptomatology. A cross-over limb was also attempted, but no patient would participate. This presentation details the case history of the propositus patient and the preliminary results of the currently ongoing prospective study.
Authors:
A J Gulya; R B Sessions; T R Troost
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of otology     Volume:  13     ISSN:  0192-9763     ISO Abbreviation:  Am J Otol     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1992-12-01     Completed Date:  1992-12-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909513     Medline TA:  Am J Otol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  438-42     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, Georgetown University, Washington, DC.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aspartame / adverse effects*
Dizziness / chemically induced*,  epidemiology
Female
Humans
Prevalence
Prospective Studies
Chemical
Reg. No./Substance:
22839-47-0/Aspartame

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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