Document Detail

Asessment of fetal gestational age in high-risk pregnancies by amniotic fluid analyses and ultrasound mensuration.
MedLine Citation:
PMID:  686108     Owner:  NLM     Status:  MEDLINE    
Maturity studies are reported on 204 women with high-risk pregnancies. Estimates of fetal maturity were made prenatally by the use of ultrasonic measurements, the lecithin/sphingomyelin (L/S) ratio, and a gestational index based on amniotic fluid creatinine, urea nitrogen, and cytology. These estimates were compared with the neonatal pediatric estimate of maturity. The gestational score agreed with pediatric maturity to within 14 days in 95 per cent of the cases. Estimates of L/S ratio distinguished between mature and immature infants in 86 per cent of the cases. Ultrasound could estimate gestational age only to within 14 days in 75 per cent of the cases, and the disagreements were greatest where either growth retardation or macrosomia was present. However, ultrasound is more useful in estimating fetal size and abnormalities of growth pattern. An estimate of gestational age by gestational score aids management, particularly where growth retardation is present, enabling a decision about delivery to be made even though the infant is very small and has an immature L/S ratio.
E G Robertson; K K Holsinger; K J Neer; S J Garcia
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  132     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1978 Sep 
Date Detail:
Created Date:  1978-10-25     Completed Date:  1978-10-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  192-7     Citation Subset:  AIM; IM    
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MeSH Terms
Amniotic Fluid / analysis*,  cytology
Creatinine / analysis
Evaluation Studies as Topic
Gestational Age*
Nitrogen / analysis
Phosphatidylcholines / analysis
Pregnancy Complications*
Sphingomyelins / analysis
Reg. No./Substance:
0/Phosphatidylcholines; 0/Sphingomyelins; 60-27-5/Creatinine; 7727-37-9/Nitrogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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