Document Detail

Aseptic meningo-radiculo-encephalitis presenting initially with urinary retention: a variant of acute disseminated encephalomyelitis.
MedLine Citation:
PMID:  16502219     Owner:  NLM     Status:  MEDLINE    
We report three male patients with aseptic meningoencephalo- radiculitis presenting with acute urinary retention. Viral antibody titers for herpes types I and II and the PCR studies were negative. The cerebrospinal fluid revealed elevated myelin basic protein. The serum antibodies against a panel of gangliosides, some of which are known to be associated with acquired demyelinating neuropathies, were all negative. The magnetic resonance imaging (MRI) studies revealed spotty T2 high intensities in the basal ganglia, thalamus and brainstem in two patients. In one patient,meningeal gadolinium enhancement of the conus and cauda equina of the spinal cord was recognized. On urodynamic studies, all patients showed features of atonic bladder with or without detrusor hyperactivity. They were treated conservatively without using steroids or immunoglobulins, and made a remarkable functional recovery with the disappearance of abnormal MRI findings.However, all three were left with erectile dysfunction, and two continued to use self-intermittent catheterization at more than 3-year follow-up. There was no recurrence of symptoms. The underlying causes remain unclear, though they may represent a variant of acute disseminated encephalomyelitis.
M Sasaki; S Ohara; R Hayashi; T Iwahashi; J Tsuyuzaki
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-03-06
Journal Detail:
Title:  Journal of neurology     Volume:  253     ISSN:  0340-5354     ISO Abbreviation:  J. Neurol.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-21     Completed Date:  2007-03-16     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  0423161     Medline TA:  J Neurol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  908-13     Citation Subset:  IM    
Department of Neurology, National Chushin-Matsumoto Hospital, 811 Kotobuki, Matsumoto, Japan.
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MeSH Terms
Autoantibodies / blood
Brain / pathology,  physiopathology
Central Nervous System / pathology*,  physiopathology
Consciousness Disorders / pathology,  physiopathology
Cranial Nerve Diseases / pathology,  physiopathology
Disease Progression
Encephalomyelitis, Acute Disseminated / pathology*,  physiopathology
Erectile Dysfunction / pathology,  physiopathology
Leukocyte Count
Magnetic Resonance Imaging
Meningitis, Aseptic / pathology*,  physiopathology
Middle Aged
Paresis / pathology,  physiopathology
Polyradiculopathy / pathology,  physiopathology
Quadriplegia / pathology,  physiopathology
Radiculopathy / pathology*,  physiopathology
Spinal Cord Compression / pathology,  physiopathology
Urinary Bladder, Neurogenic / pathology,  physiopathology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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