Document Detail

Ascorbic acid and tyrosine metabolism in preterm and small-for-dates infants.
MedLine Citation:
PMID:  1147657     Owner:  NLM     Status:  MEDLINE    
Ascorbic acid levels in plasma and leucocytes and urinary excretion of tyrosyl derivatives (TD) were determined in 11 normal, 18 preterm, and 4 small-for-dates infants. Concentrations of ascorbic acid in both plasma and leucocytes were found to be similar in the 3 groups. There was no difference in the basal levels of TD between normal and small-for-dates infants, but preterms showed higher basal excretion of TD than the other two groups. After protein load the excretion of TD was higher than the basal level in preterms. It was concluded that the altered metabolism of tyrosine observed in preterms is not the result of poor ascorbic acid status; and that tyrosine metabolism is influenced by the period of gestation rather than the body weight of the infant.
M Mohanram; A Kumar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  50     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1975 Mar 
Date Detail:
Created Date:  1975-10-07     Completed Date:  1975-10-07     Revised Date:  2010-09-09    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  235-7     Citation Subset:  IM    
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MeSH Terms
Ascorbic Acid / blood,  metabolism*
Birth Weight
Creatinine / urine
Gestational Age
Infant, Newborn*
Infant, Premature*
Leukocytes / metabolism
Tyrosine / metabolism*,  urine
Reg. No./Substance:
50-81-7/Ascorbic Acid; 55520-40-6/Tyrosine; 60-27-5/Creatinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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