Document Detail


Ascites production in 9 rat strains.
MedLine Citation:
PMID:  312305     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A simple inexpensive, and rapid method for inducing large volumes of ascitic fluid in rats is described. The procedure involves intraperitoneal injections of Freund's adjuvant emulsion on alternate days. Antibody activity of the ascitic fluid approximates that found in the serum. Female rats consistently respond better than males. Members of all 9 strains of rats tested produced ascites using this procedure.
Authors:
E G Douglas; Y Hamada; T J McKearn
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of immunological methods     Volume:  26     ISSN:  0022-1759     ISO Abbreviation:  J. Immunol. Methods     Publication Date:  1979  
Date Detail:
Created Date:  1979-07-28     Completed Date:  1979-07-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1305440     Medline TA:  J Immunol Methods     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  69-74     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Antibodies
Ascites / immunology*
Erythrocytes / immunology
Female
Immunization
Injections, Intraperitoneal
Male
Rats
Rats, Inbred ACI
Rats, Inbred BN
Rats, Inbred Lew
Sheep
Chemical
Reg. No./Substance:
0/Antibodies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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