Document Detail

Ascites not due to congestive heart failure in a fetus with lupus-induced heart block.
MedLine Citation:
PMID:  2216265     Owner:  NLM     Status:  MEDLINE    
Hydrops developing in fetuses with lupus-associated heart block has usually been assumed to result from congestive heart failure. We present a case in which fetal ascites associated with complete heart block resolved promptly after administration of betamethasone and prednisone to the mother, who had anti-SSA and who developed clinical lupus erythematosus. This resolution occurred with no demonstrable change in fetal cardiac function. We conclude that an immune mechanism, rather than congestive heart failure, was responsible for the fetal ascites.
D S Richards; A J Wagman; M L Cabaniss
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  76     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1990-11-19     Completed Date:  1990-11-19     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  957-9     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville.
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MeSH Terms
Ascites / etiology*
Betamethasone / therapeutic use
Fetal Diseases / etiology*
Fetal Heart / physiology
Heart Block / etiology*
Heart Failure*
Lupus Erythematosus, Systemic / complications*,  drug therapy
Prednisone / therapeutic use
Pregnancy Complications* / drug therapy
Reg. No./Substance:
378-44-9/Betamethasone; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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