Document Detail


Ascending aortic blood pressure waveform may be related to the risk of coronary artery disease in women, but not in men.
MedLine Citation:
PMID:  15042115     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recent studies have demonstrated that fractional pulse pressure and fractional diastolic pressure are related to the risk of coronary artery disease. However, the effect of the ascending aortic pressure waveform on the risk of coronary artery disease in men and women analyzed separately has not been reported. The objective of the study was to assess the relation between ascending aortic blood pressure waveform and the presence of coronary artery disease in men and in women. The study group consisted of 447 patients (302 men and 145 women; mean age: 57.6+/-9.8 years) with preserved left ventricular function who were undergoing first diagnostic coronary angiography. After multivariate stepwise adjustments, the odds ratio (OR) and confidence interval (CI) of having coronary artery disease in women was (OR are reported for standard deviation increase in each variable): pulse pressure OR 1.61 (95% CI 1.06-2.46); fractional systolic pressure OR 1.72 (95% CI 1.08-2.71); fractional diastolic pressure OR 0.58 (95% CI 0.37-0.92); fractional pulse pressure OR 1.72 (95% CI 1.08-2.71); and pulsatility index OR 1.74 (95% CI 1.09-2.78). None of the studied variables was independently related to the presence of coronary artery disease in men. In conclusion, fractional systolic and diastolic pressure, pulse pressure, fractional pulse pressure and the ratio of pulse pressure to diastolic pressure may be independently related to the risk of coronary artery disease in women, but not in men.
Authors:
P Jankowski; K Kawecka-Jaszcz; D Czarnecka; L Bryniarski
Related Documents :
1727815 - Markers of sodium and volume homeostasis in pregnancy-induced hypertension.
8855575 - Distribution of blood pressure and influence of subcutaneous fat on systolic and diasto...
9204695 - Psychosocial factors in blood pressure variation: a comparative study of young samoans.
16467415 - Adult blood pressure and climate conditions in infancy: a test of the hypothesis that d...
16156375 - Glucocorticoid hypertension due to the use of bleaching skin cream, a case report.
12620695 - Left ventricular mass regression in the life study: effect of previous antihypertensive...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of human hypertension     Volume:  18     ISSN:  0950-9240     ISO Abbreviation:  J Hum Hypertens     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-08-23     Completed Date:  2006-07-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8811625     Medline TA:  J Hum Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  643-8     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Collegium Medicum Jagiellonian University, ul. Kopernika 17, 31-501 Kraków, Poland. piotr_jankowski@interia.pl
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Aorta* / physiopathology
Blood Pressure*
Coronary Angiography
Coronary Artery Disease / physiopathology*,  radiography
Female
Humans
Male
Middle Aged
Multivariate Analysis
Myocardial Contraction
Odds Ratio
Poland / epidemiology
Pulsatile Flow*
Research Design
Risk Factors
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Once-daily eprosartan mesylate in the treatment of elderly patients with isolated systolic hypertens...
Next Document:  Sex-related difference in regression of left ventricular hypertrophy with antihypertensive treatment...