Document Detail


Asbestos exposure and malignant lymphomas--a review of the epidemiological literature.
MedLine Citation:
PMID:  11697448     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There has been a significant number of case reports on the occurrence of lymphomas in people previously exposed to asbestos. This raises the question of whether corresponding results are available from analytical epidemiological studies. In the present review of the epidemiological literature, we describe the results of the six cohort and 16 case-control studies that - according to our research - were published up to 1999 and, directly or indirectly. shed light on the above question. In summarizing the results of these studies, we have distinguished between non-Hodgkin lymphoma (NHL), chronic lymphatic leukemia (CLL) and plasmocytoma/ multiple myeloma (MM). A causal relationship between asbestos exposure and the subsequent development of lymphomas cannot be derived from the available results. However, since quite a number of studies and the combined analysis indicate a (weakly) increased risk, this question should be considered directly in future epidemiological studies. Such studies should address separately the various sub-entities, employing the latest internationally agreed classification, and should also use the latest methods of quantifying exposure.
Authors:
N Becker; J Berger; U Bolm-Audorff
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International archives of occupational and environmental health     Volume:  74     ISSN:  0340-0131     ISO Abbreviation:  Int Arch Occup Environ Health     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-11-07     Completed Date:  2002-01-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7512134     Medline TA:  Int Arch Occup Environ Health     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  459-69     Citation Subset:  IM    
Affiliation:
Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Asbestos*
Case-Control Studies
Causality
Cohort Studies
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / epidemiology
Lymphoma / epidemiology*
Lymphoma, Non-Hodgkin / epidemiology
Occupational Exposure*
Odds Ratio
Plasmacytoma / epidemiology
Chemical
Reg. No./Substance:
1332-21-4/Asbestos

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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