| Artificially produced meteorological changes aggravate pain in adjuvant-induced arthritic rats. | |
| | |
MedLine Citation:
|
PMID: 14698479 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To examine the effects of change in meteorological parameters on pain-related behaviors in a simulated arthritic condition, rats with an injection of complete Freund's adjuvant into the tibio-tarsal joint were exposed to low barometric pressure (20 mmHg below the natural atmospheric pressure) and low ambient temperature (7 degrees C lower than 22 degrees C) in a climate-controlled room. When the arthritic rats were exposed to these environments, the already increased number of hindpaw withdrawals in response to noxious mechanical stimulation (hyperalgesia) was further increased, and a hindpaw withdrawal response to innocuous mechanical stimulation (allodynia) began to occur. Such exposures did not influence any of the pain-related behaviors of the control rats. These results show that lowering barometric pressure and ambient temperature within the range of natural environmental fluctuation intensify pain in arthritic rats. |
| | |
Authors:
|
Jun Sato; Morihiko Aoyama; Masahiro Yamazaki; Satoshi Okumura; Ken Takahashi; Megumi Funakubo; Kazue Mizumura |
Related Documents
:
|
7124929 - A reexamination of the effects of high rearing temperature on the nonolfactory turbinat... 446769 - The function of glucocorticoids in thermogenesis. 525249 - Hybridization and heat tolerance in rats. 7477949 - Temperature change-induced potentiation: a comparative study of facilitatory mechanisms... 2097169 - Body temperature rhythms, cold tolerance, and fever in young and old rats of both genders. 7849919 - Influence of perflubron emulsion particle size on blood half-life and febrile response ... 9835219 - Increased ciliary neurotrophic factor expression in reactive astrocytes following spina... 8537419 - The effect of smoke inhalation on bradykinin metabolism by the perfused and ventilated ... 8742319 - Subchronic effects of dieldrin and phenobarbital on hepatic dna synthesis in mice and r... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Neuroscience letters Volume: 354 ISSN: 0304-3940 ISO Abbreviation: Neurosci. Lett. Publication Date: 2004 Jan |
Date Detail:
|
Created Date: 2003-12-30 Completed Date: 2004-02-26 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 7600130 Medline TA: Neurosci Lett Country: Ireland |
Other Details:
|
Languages: eng Pagination: 46-9 Citation Subset: IM |
Affiliation:
|
Department of Neural Regulation, Research Institute of Environmental Medicine, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan. jun@riem.nagoya-u.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Arthritis, Experimental / physiopathology* Atmospheric Pressure Cold Temperature Hyperalgesia / physiopathology* Male Pain / physiopathology* Pain Measurement Rats Rats, Sprague-Dawley Weather* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Neural networks engaged in short-term memory rehearsal are disrupted by irrelevant speech in human s...
Next Document: Evidence from brain imaging with fMRI supporting functional specificity of acupoints in humans.