Document Detail

Artificial endometrial preparation for oocyte donation using synthetic estrogen and progestogen.
MedLine Citation:
PMID:  9856304     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the outcome of an oocyte donation program using synthetic estrogen and progestational agents for uterine preparation. METHODS: Conjugated estrogen, 1.25 mg per day at increasing doses and dydrogesterone, a synthetic progestogen, 30 mg per day were used for uterine priming. All embryo transfers were done on day 2 of progestogen supplementation. RESULTS: The pregnancy rates were 38% per embryo transfer. The ongoing pregnancy rate was 31% with an abortion rate of 20%. CONCLUSION: Endometrial preparation in an oocyte donation program using orally administered synthetic estrogen and progestogen gives pregnancy rates comparable to those reported with natural products.
A Abu-Musa; A Hannoun; A Khalil; Z Masaad; K Karam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental obstetrics & gynecology     Volume:  25     ISSN:  0390-6663     ISO Abbreviation:  Clin Exp Obstet Gynecol     Publication Date:  1998  
Date Detail:
Created Date:  1999-02-19     Completed Date:  1999-02-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802110     Medline TA:  Clin Exp Obstet Gynecol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  83-5     Citation Subset:  IM    
Department of Obstetrics and Gynecology, American University of Beirut-Medical Center, Lebanon.
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MeSH Terms
Buserelin / administration & dosage
Chorionic Gonadotropin / administration & dosage
Dydrogesterone / administration & dosage*
Embryo Transfer
Endometrium / physiology*
Estradiol / blood
Estrogens, Conjugated (USP) / administration & dosage*
Menotropins / administration & dosage
Oocyte Donation*
Ovarian Failure, Premature
Ovarian Follicle / ultrasonography
Progesterone Congeners*
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Estrogens, Conjugated (USP); 0/Progesterone Congeners; 152-62-5/Dydrogesterone; 50-28-2/Estradiol; 57982-77-1/Buserelin; 61489-71-2/Menotropins

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