Document Detail


Artificial cell microcapsules containing genetically engineered E. coli DH5 cells for in-vitro lowering of plasma potassium, phosphate, magnesium, sodium, chloride, uric acid, cholesterol, and creatinine: a preliminary report.
MedLine Citation:
PMID:  10595451     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lowering of plasma Mg, P, Na, Cl, uric acid, cholesterol, and creatinine is required in renal failure and other diseases. In this preliminary report, we studied the ability of artificial cells microencapsulated genetically engineered E. coli DH5 cells in lower K, Mg, P, Na, Cl, uric acid, cholestrol, creatinine, and billirubin from plasma in-vitro. Result shows that this novel approach has the ability to significantly lower these metabolites from the plasma in-vitro.
Authors:
S Prakash; T M Chang
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Artificial cells, blood substitutes, and immobilization biotechnology     Volume:  27     ISSN:  1073-1199     ISO Abbreviation:  Artif Cells Blood Substit Immobil Biotechnol     Publication Date:    1999 Sep-Nov
Date Detail:
Created Date:  2000-01-19     Completed Date:  2000-01-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9431307     Medline TA:  Artif Cells Blood Substit Immobil Biotechnol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  475-81     Citation Subset:  IM    
Affiliation:
Artificial Cells and Organs Research Centre, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.
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MeSH Terms
Descriptor/Qualifier:
Animals
Biomass
Capsules
Chlorides / blood
Cholesterol / blood*
Creatinine / blood*
Electrolytes / blood*
Escherichia coli / cytology*
Genetic Engineering
Magnesium / blood
Male
Membranes, Artificial*
Phosphates / blood
Potassium / blood
Rats
Rats, Wistar
Sodium / blood
Urease / metabolism
Uric Acid / blood*
Chemical
Reg. No./Substance:
0/Capsules; 0/Chlorides; 0/Electrolytes; 0/Membranes, Artificial; 0/Phosphates; 57-88-5/Cholesterol; 60-27-5/Creatinine; 69-93-2/Uric Acid; 7439-95-4/Magnesium; 7440-09-7/Potassium; 7440-23-5/Sodium; EC 3.5.1.5/Urease

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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