Document Detail

Artifacts and organism mimickers in pathology: case examples and review of literature.
MedLine Citation:
PMID:  20574173     Owner:  NLM     Status:  MEDLINE    
Despite the impressive advances in pathology and microbiology of recent years, the morphologic recognition of an organism remains a major component in rendering a specific diagnosis of an infectious process, or at minimum, a trigger in the process of identifying an infectious agent. Artifacts and mimickers may pose difficulty to the unwary, and may cause a potential "wild goose chase" that can result in wasted valuable time and resources. Fibrin, collagen exogenous fibers, and bacteria may mimic fungal hyphae. Morphologically altered or treated bacteria and Russel bodies may be mistaken for fungal yeasts, etc. Examples of artifacts and mimickers that may simulate infectious organisms are presented in this article. In addition, a review of literature on the subject, demonstrating a surprising dearth of published articles, despite the frequent encounters of this issue in the daily practice.
Saeeda Almarzooqi; Amy Leber; Samir Kahwash
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances in anatomic pathology     Volume:  17     ISSN:  1533-4031     ISO Abbreviation:  Adv Anat Pathol     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-24     Completed Date:  2010-08-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9435676     Medline TA:  Adv Anat Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  277-81     Citation Subset:  IM    
Department of Pathology, Nationwide Children's Hospital, Columbus, OH, USA.
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MeSH Terms
Bacterial Infections / pathology
Diagnosis, Differential
Diagnostic Errors*
Mycoses / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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