| Articular manifestations of polymyositis and dermatomyositis. | |
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MedLine Citation:
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PMID: 463935 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nine patients with polymyositis or dermatomyositis associated with arthritis without antinuclear antibodies have been studied. In eight patients a mildly inflammatory nonerosive arthritis occurred coincident with early manifestations or before the appearance of symptomatic muscle disease. Hands, wrists and knees were prominently involved. This arthritis responded to corticosteroids given for the myositis. One patient had erosive arthritis and periarticular calcifications associated with acute inflammation that seemed to diminish with colchicine therapy. Synovial biopsy specimens showed surface fibrin deposition, focal loss of lining cells and mild inflammation--findings similar to those in scleroderma. By electron microscopy tubuloreticular structures were found in vascular endothelium in synovium, as in other tissues in polymyositis. All patients surprisingly had pulmonary manifestations suggesting the possibility that the condition in this group of patients may represent a distinctive subset of polymyositis. |
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Authors:
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H R Schumacher; B Schimmer; G V Gordon; M A Bookspan; S Brogadir; B B Dorwart |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of medicine Volume: 67 ISSN: 0002-9343 ISO Abbreviation: Am. J. Med. Publication Date: 1979 Aug |
Date Detail:
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Created Date: 1979-09-25 Completed Date: 1979-09-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0267200 Medline TA: Am J Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 287-92 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Arthritis / etiology* Biopsy Dermatomyositis / complications, diagnosis* Female Humans Male Middle Aged Myositis / complications, diagnosis* Synovial Fluid / analysis Synovial Membrane / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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