| Arthroscopic and histologic findings in Morquio's syndrome. | |
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MedLine Citation:
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PMID: 15689875 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mucopolysaccharidosis type IV A/B (Morquio's syndrome) is one of a heterogeneous group of lysosomal storage diseases characterized by accumulation of keratan sulfate in cells of connective tissue. From early childhood, the major orthopaedic manifestations are shortening of the trunk, spondylepiphyseal dysplasia, odontoid hypoplasia, upper cervical instability, lower-limb alignment problems, and degenerative joint disease. Most of the rare published case reports describe those characteristic clinical deformities of the skeleton. Our literature search showed that these striking arthroscopic findings have not been made public to date. We report a typical case of mucopolysaccharidosis type IV. We show and, in particular, correlate the arthroscopic with the histologic findings. In particular, the comparison between arthroscopy and light microscopy showed a remarkable extensive delamination of the chondral layer from subchondral bone of both knee joints. These findings should encourage further research, especially of the osteochondral borderline. |
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Authors:
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Thomas Kalteis; Thomas Schubert; Wolfgang Christopher Caro; Josef Schröder; Christian Lüring; Joachim Grifka |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association Volume: 21 ISSN: 1526-3231 ISO Abbreviation: Arthroscopy Publication Date: 2005 Feb |
Date Detail:
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Created Date: 2005-02-03 Completed Date: 2006-02-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8506498 Medline TA: Arthroscopy Country: United States |
Other Details:
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Languages: eng Pagination: 233-7 Citation Subset: IM |
Affiliation:
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Department of Orthopaedic Surgery, the University of Regensburg, Regensburg, Germany. thomas.kalteis@klinik.uni-regensburg.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Arthroscopy Cartilage, Articular / pathology* Female Humans Knee Joint / pathology* Mucopolysaccharidosis IV / pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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