Document Detail


Arthritis associated with jejunoileal bypass: clinical and immunologic evaluation.
MedLine Citation:
PMID:  313212     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Arthritis is a common complication of small bowel bypass, occurring in 5-20% of the postsurgical patients. Thirteen patients with arthritis related to jejunoileal bypass were studied. These patients had a symmetrical polyarthritis, and 8 also had extraarticular connective tissue disease manifestations. Immunologic evaluations were done on these patients and on a control group of 12 age- and sex-matched postintestinal bypass patients without arthritis. The incidence of positive ANA, rheumatoid factors, immune complexes, and antibodies to intestinal flora was the same in both groups. Patients in both groups showed similar changes in numbers of circulating T and B lymphocytes. More patients in the group with arthritis than in the control group had elevated IgA levels (38% versus 8%), but the difference was not significant (P less than 0.05). This study demonstrates that immunologic abnormalities occur after jejeunoileal bypass irrespective of the onset of arthritis or related symptoms. No specific immunologic abnormalities could be associated with the arthritis occurring after small bowel bypass.
Authors:
M Zapanta; M Aldo-Benson; A Biegel; J Madura
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Arthritis and rheumatism     Volume:  22     ISSN:  0004-3591     ISO Abbreviation:  Arthritis Rheum.     Publication Date:  1979 Jul 
Date Detail:
Created Date:  1979-09-01     Completed Date:  1979-09-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370605     Medline TA:  Arthritis Rheum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  711-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Antibodies, Antinuclear* / analysis
Antibodies, Bacterial* / analysis
Antigen-Antibody Complex*
Arthritis / diagnosis,  etiology*,  immunology
B-Lymphocytes* / immunology
Complement C3 / analysis
Complement C4 / analysis
Cryoglobulins* / analysis
Female
Humans
Immunoglobulin A / analysis
Immunoglobulins* / analysis
Intestine, Small / surgery*
Male
Obesity / therapy*
Rheumatoid Factor* / analysis
Rosette Formation
Skin Tests
T-Lymphocytes* / immunology
Chemical
Reg. No./Substance:
0/Antibodies, Antinuclear; 0/Antibodies, Bacterial; 0/Antigen-Antibody Complex; 0/Complement C3; 0/Complement C4; 0/Cryoglobulins; 0/Immunoglobulin A; 0/Immunoglobulins; 9009-79-4/Rheumatoid Factor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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