Document Detail


Arteritis following intra-arterial chemotherapy for liver tumors.
MedLine Citation:
PMID:  9087350     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primary and metastatic tumors of the liver can be treated successfully with transcatheter chemoembolization (TACE) during selective arterial catheterism. Arteritis is a possible referred side effect which can lead to tortuosity of the arteries, stenosis and occlusion of vessels. In our hospitals 117 consecutive patients were treated with TACE from January 1990 to December 1992; 61 patients were affected by hepatocellular carcinoma (HCC) and 56 were affected by metastases from colorectal carcinoma. Each patient received from 1 to 4 treatments at monthly intervals using epirubicin/Lipiodol ultrafluid (E/LUF) or a mixture of epirubicin and mitomicin C (MC)/LUF and followed by gelatine sponge injection in the hepatic artery. Selective angiography performed 30-62 days after the first chemoembolization showed artery stenosis in 7 patients and thrombosis in 2 cases related to toxic arteritis due to chemoembolization. Reports about arteritis during TACE treatments are discussed.
Authors:
L Belli; G Magistretti; G P Puricelli; G Damiani; E Colombo; G P Cornalba
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European radiology     Volume:  7     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  1997  
Date Detail:
Created Date:  1997-05-23     Completed Date:  1997-05-23     Revised Date:  2006-04-13    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  323-6     Citation Subset:  IM    
Affiliation:
Department of Radiology, Ospedale Multizonale, Viale Borri 57, I-21100 Varese, Italy.
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MeSH Terms
Descriptor/Qualifier:
Aged
Antibiotics, Antineoplastic / administration & dosage,  adverse effects
Arteritis / chemically induced*,  radiography
Carcinoma, Hepatocellular / therapy*
Chemoembolization, Therapeutic / adverse effects*
Epirubicin / administration & dosage,  adverse effects
Female
Gelatin Sponge, Absorbable
Hepatic Artery* / radiography
Humans
Injections, Intra-Arterial / adverse effects
Iodized Oil / administration & dosage,  adverse effects
Liver Neoplasms / therapy*
Male
Middle Aged
Mitomycin / administration & dosage
Chemical
Reg. No./Substance:
0/Antibiotics, Antineoplastic; 50-07-7/Mitomycin; 56420-45-2/Epirubicin; 8001-40-9/Iodized Oil

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