Document Detail


Arteritis of both carotid arteries in a patient with focal, crescentic glomerulonephritis and anti-neutrophil cytoplasmic autoantibodies.
MedLine Citation:
PMID:  8162485     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a 32-yr-old woman who suffered a stroke as a consequence of arteritis of both internal carotid arteries confirmed by selective carotid arteriography. Laryngeal inflammation and kidney biopsy proven focal crescentic glomerulonephritis were also present in this patient. Anti-neutrophil cytoplasmic autoantibodies with specificity for proteinase 3 were detected in high titre during the active phase of the disease. This overlap syndrome with features indicating both Takayasu's arteritis and Wegener's granulomatosis suggests a common pathogenesis for these diseases.
Authors:
D Logar; B Rozman; A Vizjak; D Ferluga; A H Mulder; C G Kallenberg
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  British journal of rheumatology     Volume:  33     ISSN:  0263-7103     ISO Abbreviation:  Br. J. Rheumatol.     Publication Date:  1994 Feb 
Date Detail:
Created Date:  1994-05-26     Completed Date:  1994-05-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8302415     Medline TA:  Br J Rheumatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  167-9     Citation Subset:  AIM; IM    
Affiliation:
University Medical Centre, Department of Rheumatology, Ljubljana, Slovenia.
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MeSH Terms
Descriptor/Qualifier:
Adult
Angiography
Antibodies, Antineutrophil Cytoplasmic
Antibody Specificity
Arteritis / complications*,  immunology,  pathology*
Autoantibodies / analysis*
Carotid Arteries / pathology*,  radiography
Female
Glomerulosclerosis, Focal Segmental / complications*,  immunology*,  pathology
Humans
Chemical
Reg. No./Substance:
0/Antibodies, Antineutrophil Cytoplasmic; 0/Autoantibodies

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