Document Detail


Arteriovenous fistula, blood flow, cardiac output, and left ventricle load in hemodialysis patients.
MedLine Citation:
PMID:  20449895     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to investigate an association between vascular access blood flow (QVA), cardiac output(CO), and load of left ventricle (LLV) using a simple physical model calculation based on real data, specifically inpatients with high access blood flow arteriovenous fistula(AVF). Vascular access blood flow, CO, and peripheral vascular resistance (PR) were determined by ultrasound dilution technique (HD01; Transonic Systems, Inc., Ithaca, NY). Load of left ventricle was calculated using simplified formula: LLV x PR CO2. This total load was computationally divided into the part spent to run the flow QVA through the AVF (LLVAVF) and that part ensuring the flow (CO-QVA) through the vascular system. The model calculation was first performed in a selected group of 15 patients with high access blood flow (QVA >1,300 ml/min, group 1) and later extended for comparison by another group of 40 unselected patients with access blood flow in lower range (QVA range 200-1,400 ml/min, group 2).Mean LLV in group 1 was 2.10 +/- 0.68 W. LLV(AVF) was 21.8% of total LLV. Mean LLV in group 2 was 1.2 +/- 0.5 W.LLVAVF was 11.1% of total LLV. Our computational results suggest that AVF in typical range of QVA shall not increase heart load significantly.
Authors:
Martin Válek; Frantisek Lopot; Vladimír Polakovic
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  ASAIO journal (American Society for Artificial Internal Organs : 1992)     Volume:  56     ISSN:  1538-943X     ISO Abbreviation:  ASAIO J.     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-05-06     Completed Date:  2010-08-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204109     Medline TA:  ASAIO J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  200-3     Citation Subset:  IM    
Affiliation:
2nd Department of Internal Medicine,1st Faculty of Medicine, Charles University, U Nemocnice 2, 12808 Prague 2, Czech Republic. m.valek@seznam.cz
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MeSH Terms
Descriptor/Qualifier:
Adult
Cardiac Output / physiology*
Drug Administration Routes
Female
Heart Catheterization
Heart Ventricles / physiopathology
Hemodynamics*
Humans
Indicator Dilution Techniques
Male
Middle Aged
Renal Dialysis / methods*
Vascular Resistance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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